Evidence map›Paper›PMID 35854999›Full record

ArticleOpen forum infectious diseases2022

Human Herpesvirus-6 Detection in Cerebrospinal Fluid on the BioFire FilmArray Meningitis/Encephalitis Panel in a High Human Immunodeficiency Virus-Prevalence African Setting.

James Milburn, Kwana Lechiile, Keatlaretse Siamisang, Christopher G Williams, Leah Owen, Ezekiel Gwakuba, Tichaona Machiya, Tshepo Leeme, Hannah E Barton, Ronan Doyle and 5 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

James MilburnBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.ORCID https://orcid.org/0000-0001-9885-6103
Kwana LechiileBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Keatlaretse SiamisangBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Christopher G WilliamsBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Leah OwenBotswana-UPenn Partnership, Gaborone, Botswana.
Ezekiel GwakubaDepartment of Medical Laboratory Science, Faculty of Health Sciences, University of Botswana, Gaborone, Botswana.
Tichaona MachiyaMicrobiology Department, Princess Marina Hospital, Gaborone, Botswana.
Tshepo LeemeBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Hannah E BartonBotswana-UPenn Partnership, Gaborone, Botswana.
Ronan DoyleDepartment of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
Mark W TenfordeBotswana-UPenn Partnership, Gaborone, Botswana.
Madisa MineNational Health Laboratory, Gaborone, Botswana.
David M GoldfarbDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.
Margaret MokomaneDepartment of Medical Laboratory Science, Faculty of Health Sciences, University of Botswana, Gaborone, Botswana.
Joseph N JarvisBotswana Harvard AIDS Institute Partnership, Gaborone, Botswana.
Botswana Harvard AIDS Institute Partnership · BWBotswana Open University · BWLondon School of Hygiene & Tropical Medicine · GBUniversity of Botswana · BWUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence and clinical relevance of human herpesvirus-6 (HHV-6) detection in cerebrospinal fluid (CSF) using multiplex polymerase chain reaction (PCR) testing in patients with suspected meningoencephalitis in high human immunodeficiency virus-prevalence African settings are not known. We describe the clinical and laboratory characteristics of 13 patients with HHV-6 CSF PCR positivity in Botswana.

Indexed as

cerebrospinal fluidencephalitisHIVhuman herpesvirus-6meningitis

Identifiers

PMID35854999
PMCPMC9280324
OpenAlexW4280505284

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.