Evidence map›Paper›PMID 35854966›Full record

ArticleTranslational animal science2022

Immunomodulatory potential of black soldier fly larvae: applications beyond nutrition in animal feeding programs.

Elizabeth Koutsos, Bree Modica, Tarra Freel

Abstract read
In one paragraph

Article in Translational animal science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Review
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  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Medium-Chain Fatty Acids Extracted from Black Soldier Fly (Animals : an open access journal from MDPI · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elizabeth KoutsosEnviroFlight, LLC, 1118 Progress Way, Maysville, KY 41056, USA.
Bree ModicaEnviroFlight, LLC, 1118 Progress Way, Maysville, KY 41056, USA.
Tarra FreelEnviroFlight, LLC, 1118 Progress Way, Maysville, KY 41056, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insect-derived ingredients, including whole larvae, protein-rich meal, and oil, have been extensively studied in recent years and shown to be a sustainable source of quality nutrition for virtually all animal species and life stages. In addition to the ability to use these ingredients as a source of essential nutrition, more recent research has demonstrated the potential for the immunomodulatory activity of various components of insect-derived ingredients. For all insects studied, antimicrobial peptides make up a critical part of the insects' innate immune system and these peptides have antimicrobial efficacy when purified from hemolymph and tested in vitro. From black soldier fly larvae, in particular, lauric acid is a predominant fatty acid deposited into the insect, and lauric acid also has potential antimicrobial activity in vitro and in vivo. Finally, the chitin and chitosan components of the insect exoskeleton may modulate microbial activity in a variety of ways. In companion animals, poultry, and livestock species, insect-derived ingredients have shown the potential to reduce the impact of actual or simulated disease challenge on several parameters of animal health and well-being. This review describes the current state of knowledge of the immunomodulatory potential of insect-derived ingredients.

Indexed as

antimicrobial peptidesblack soldier flychitinimmunomodulatorylauric acidnutrition

Identifiers

PMID35854966
PMCPMC9280983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.