Evidence map›Paper›PMID 35854950›Full record

ArticleJournal of neurosurgery. Case lessons2021

Gout in the thoracic spine causing acute paraplegia: illustrative case.

Lacin Koro, Ryan Khanna, Dominick Richards, Dean G Karahalios

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Journal of neurosurgery. Case lessons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Diagnostic challenges of spinal gout: patient series.Journal of neurosurgery. Case lessons · 2025
    Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Lacin KoroDepartment of Neurological Surgery, Rush University Medical Center, Chicago, Illinois; and.
Ryan KhannaDepartment of Neurological Surgery, Rush University Medical Center, Chicago, Illinois; and.
Dominick RichardsDepartment of Neurological Surgery, Rush University Medical Center, Chicago, Illinois; and.
Dean G KarahaliosBrain & Spine Institute, Advocate Aurora Health, Downers Grove, Illinois.
Neurological Surgery · USAdvocate Health Care · USRush University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough spinal involvement by gout is not uncommon, spinal gout leading to symptomatic spinal cord compression in the thoracic spine is very rare and poses a diagnostic challenge by mimicking symptoms of more common diagnoses such as epidural abscess and malignancy. An even more unique presentation is spinal gout causing thoracic cord compression leading to acute paraplegia. OBSERVATIONS: The authors present an illustrative case of a 35-year-old man with thoracic spinal compression by tophaceous gout who developed rapid progression to complete paraplegia over a 5-day period. Magnetic resonance imaging of the thoracic spine revealed a cystic-appearing lesion within the dorsal extradural space of the lower thoracic spine extending from T8 to T10 accompanied by compression of the spinal cord. An emergent T9-10 laminectomy was performed, and the occupying lesion in the thoracic spine was resected. The diagnosis of spinal tophaceous gout was made by pathological examination. LESSONS: Although varying clinical manifestations of spinal gout have been reported in the literature, the patient's age and the rapid progression to complete paraplegia over a 5-day period reveals a unique presentation that broadens understanding of the manner in which this condition can present and allow more rapid diagnosis and treatment.

Indexed as

acute paraplegiaCRP = C-reactive proteinESR = erythrocyte sedimentation ratespinal goutthoracic spinal cord compressiontophus

Identifiers

PMID35854950
PMCPMC9265203
OpenAlexW3196333128

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.