Evidence map›Paper›PMID 35854771›Full record

ArticleContrast media & molecular imaging2022

Scanning Probe Microscopy Bone Marrow Determination of Steogenic Differentiation of Mesenchymal Stem Cells.

Xiandong Fu, Qixin Lian, Bo Zhang, Xinli Teng, Ying Chen, Yikun Qu, Zhuoxin Cheng, Linqi Guo

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Contrast media & molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xiandong FuThe First Affiliated Hospital of Jiamusi University, Department of General Surgery, Jiamusi 154000, China.ORCID 0000-0002-4391-7156
Qixin LianThe First Affiliated Hospital of Jiamusi University, Department of Tumour Surgery, Jiamusi 154000, China.ORCID 0000-0003-3702-5394
Bo ZhangJiamusi University, Department of Pathophysiology, Jiamusi 154000, China.ORCID 0000-0003-0334-3036
Xinli TengThe Tumor Hospital of Jiamusi, Department of Tumor, Jiamusi 154000, China.ORCID 0000-0002-9390-8493
Ying ChenThe First Affiliated Hospital of Jiamusi University, Intensive Care Unit, Jiamusi 154000, China.ORCID 0000-0003-0683-9192
Yikun QuThe First Affiliated Hospital of Jiamusi University, Department of General Surgery, Jiamusi 154000, China.ORCID 0000-0003-0061-5040
Zhuoxin ChengThe First Affiliated Hospital of Jiamusi University, Department of General Surgery, Jiamusi 154000, China.ORCID 0000-0002-1164-9222
Linqi GuoThe First Affiliated Hospital of Jiamusi University, Department of General Surgery, Jiamusi 154000, China.ORCID 0000-0002-3381-9579
Jiamusi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To address the question of determining the osteogenic differentiation of mesenchymal stem cells, the bone marrow studies were performed using probe microscopy. All adherent bone marrow was used to isolate the bone marrow mesenchymal stem cells and expanded and purified in vitro. Its morphology under an inverted microscope was observed. We used Zuogui Pills to differentiate the separation methods. Alcian blue staining, modified calcium cobalt alkaline phosphatase staining, and neuron-specific enolase immunohistochemical staining were performed. The experimental results are shown below. The morphology of the isolated and purified cells was analyzed with an inverted microscope, and the isolated and purified cells were analyzed with Zuogui Pill. Alcian blue staining, modified calcium cobalt alkaline phosphatase staining, and neuron-specific enolase immunohistochemical staining confirmed that the cells differentiated into cartilage and osteoblasts, and the cell structure and morphology were similar to those of the bone marrow mesenchymal stem cells. The results showed that the adherent mode of cells obtained from the whole bone marrow was the rat bone marrow mesenchymal stem cells, and the Zuogui Pills could induce multidirectional differences in the bone marrow mesenchymal stem cells.

Indexed as

Mesenchymal Stem CellsOsteogenesisAlcian BlueAlkaline PhosphataseAnimalsBone MarrowBone Marrow CellsCalciumCells, CulturedCobaltMicroscopy, Scanning ProbePhosphopyruvate HydrataseRatsAlcian BlueAlkaline PhosphataseCalciumCobaltPhosphopyruvate Hydratase

Identifiers

PMID35854771
PMCPMC9286954
OpenAlexW4284959920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.