Evidence map›Paper›PMID 35854691›Full record

ArticleInternational journal of cardiology. Heart & vasculature2022

Physical and psychological reconditioning in long COVID syndrome: Results of an out-of-hospital exercise and psychological - based rehabilitation program.

Silvia Compagno, Stefano Palermi, Valentina Pescatore, Erica Brugin, Marzia Sarto, Ruggero Marin, Valli Calzavara, Manuele Nizzetto, Moreno Scevola, Accurso Aloi and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 4 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 4 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Rehabilitation needs of long COVID patients in British Columbia.PM & R : the journal of injury, function, and rehabilitation · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Post-COVID Rehabilitation Outcomes: A Comparative Cohort Study.Archives of rehabilitation research and clinical translation · 2025
    Article
  14. Review
  15. Distribution of Cardiovascular Modifiable Risk Factors in a Corporate Wellness Program: A Case Study of Occupational Cardiology in the Ferrari Company.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
    Article
  16. Article
  17. Living With Long COVID: Everyday Experiences, Health Information Barriers and Patients' Quality of Life.Health expectations : an international journal of public participation in health care and health policy · 2025
    Article
  18. Article
  19. Article
  20. Reporting of pre-existing multiple long-term conditions in physical rehabilitation for long COVID: a scoping review.European respiratory review : an official journal of the European Respiratory Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Silvia CompagnoCardiovascular Rehabilitation and Sports Medicine Service, Noale - Venice, Italy.
Stefano PalermiCardiovascular Rehabilitation and Sports Medicine Service, Noale - Venice, Italy.
Valentina PescatoreCardiovascular Rehabilitation and Sports Medicine Service, Noale - Venice, Italy.
Erica BruginCardiovascular Rehabilitation and Sports Medicine Service, Noale - Venice, Italy.
Marzia SartoFederico II University Hospital, Naples, Italy.
Ruggero MarinCardiovascular Rehabilitation and Sports Medicine Service, Noale - Venice, Italy.
Valli CalzavaraCardiovascular Rehabilitation and Sports Medicine Service, Noale - Venice, Italy.
Manuele NizzettoSub-Intensive Care COVID Unit, Pneumology Service, Dolo - Venice, Italy.
Moreno ScevolaNon-critical COVID Area, Internal Medicine Service, Dolo - Venice, Italy.
Accurso AloiSub-Intensive Care COVID Unit, Pneumology Service, Dolo - Venice, Italy.
Alessandro BiffiMed-Ex, Medicine & Exercise, Medical Partner Scuderia Ferrari, Rome, Italy.
Carlo ZanellaCardiovascular Rehabilitation and Sports Medicine Service, Noale - Venice, Italy.
Giovanni CarrettaMedical Direction, Azienda ULLS 3 Serenissima, Venice, Italy.
Silvia GalloMedical Direction, Azienda ULLS 3 Serenissima, Venice, Italy.
Franco GiadaCardiovascular Rehabilitation and Sports Medicine Service, Noale - Venice, Italy.
AULSS 2 Marca Trevigiana · ITFederico II University Hospital · ITFerrari (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Long Covid Syndrome (LCS) is used to describe signs and symptoms that continue or develop after acute COVID-19 infection. Natural history and treatment of this syndrome are still poorly understood, even if evidences suggest the potential role of physical rehabilitation in improving symptoms in these patients. Aim of the study: The aim of the present study was to evaluate effectiveness, safety and feasibility of an out-of-hospital multidisciplinary rehabilitation (MDR) program, based both on physical and psychological reconditioning, in reducing symptoms and improving physical fitness and psychological parameters in patients with LCS. Methods: Thirty consecutive patients with LCS (18 males, mean age 58 years) underwent an accurate medical screening process including anthropometric and muscular strength evaluation, cardiopulmonary exercise test, quality of life (QoL) and psychological appraisal before and after a MDR program. Results: At baseline, all LCS patients were strongly symptomatic and showed severe impairments in physical performance, QoL and psychological parameters. No adverse effects and dropouts were observed during the exercise training sessions. After the MDR program, COVID-19 residual symptoms significantly decreased, and significant improvements in upper and lower limb muscular strength, cardiopulmonary parameters, perceived physical and mental health, depression and anxiety were observed. Conclusions: The present study confirms the severe physical and psychological impairment of patients with LCS and suggests that a MDR program is effective, safe and feasible in these patients and could promote their physical and psychological recovery.

Indexed as

Long covid syndromeMultidisciplinary rehabilitationPhysical exercise trainingPsychological management

Identifiers

PMID35854691
PMCPMC9286763
OpenAlexW4285586306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.