Evidence map›Paper›PMID 35854680›Full record

ArticleJournal of neurosurgery. Case lessons2021

5-Aminolevulinic acid-assisted resection of pediatric dysembryoplastic neuroepithelial tumor: illustrative case.

Luke H Beauchamp, Marian Michael Bercu, Anthony M Avellino

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Journal of neurosurgery. Case lessons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Luke H BeauchampCollege of Human Medicine, Michigan State University, East Lansing, Michigan; and.
Marian Michael BercuPediatric Neurosurgery, Helen DeVos Children's Hospital, Spectrum Health, Grand Rapids, Michigan.
Anthony M AvellinoCollege of Human Medicine, Michigan State University, East Lansing, Michigan; and.
Michigan State University · USSpectrum Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background5-Aminolevulinic acid (5-ALA) is approved as an adjunct for the resection of high-grade gliomas and is associated with improved outcomes. Dysembryoplastic neuroepithelial tumors (DNETs) are benign glioneural tumors occurring primarily in pediatric patients and often manifesting with seizure disorder. The goal of the surgical intervention is to obtain gross-total resection, which is associated, in the majority of cases, with seizure freedom. OBSERVATIONS: The authors present the first case report of a pediatric patient who underwent gross-total resection of a 5-ALA-positive DNET with no evidence of recurrent seizures (Engel class I). LESSONS: Fluorescence-guided surgery using 5-ALA facilitated gross-total resection of the mass.

Indexed as

5-ALA5-ALA = 5-aminolevulinic acid5-aminolevulinic acidDNETDNET = dysembryoplastic neuroepithelial tumordysembryoplastic neuroepithelial tumorFGS = fluorescence-guided surgeryfluorescenceGleolanIDH = isocitrate dehydrogenaseMRI = magnetic resonance imaging

Identifiers

PMID35854680
PMCPMC9265167
OpenAlexW3185722490

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.