Evidence map›Paper›PMID 35854371›Full record

ArticleTrials2022

Insecticide-treated eave nets and window screens for malaria control in Chalinze district, Tanzania: a study protocol for a household randomised control trial.

Olukayode G Odufuwa, Sarah Jane Moore, Zawadi Mageni Mboma, Emmanuel Mbuba, Joseph Barnabas Muganga, Jason Moore, Rose Philipo, Mohammed Ally Rashid, Rune Bosselmann, Ole Skovmand and 1 more

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. House modifications for preventing malaria.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Trial
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 3 countries.

Olukayode G OdufuwaVector Control Product Testing Unit, Ifakara Health Institute (IHI), Bagamoyo, Tanzania. oodufuwa@ihi.or.tz.ORCID http://orcid.org/0000-0002-3887-9394
Sarah Jane MooreVector Control Product Testing Unit, Ifakara Health Institute (IHI), Bagamoyo, Tanzania.
Zawadi Mageni MbomaVector Control Product Testing Unit, Ifakara Health Institute (IHI), Bagamoyo, Tanzania.
Emmanuel MbubaVector Control Product Testing Unit, Ifakara Health Institute (IHI), Bagamoyo, Tanzania.
Joseph Barnabas MugangaVector Control Product Testing Unit, Ifakara Health Institute (IHI), Bagamoyo, Tanzania.
Jason MooreVector Control Product Testing Unit, Ifakara Health Institute (IHI), Bagamoyo, Tanzania.
Rose PhilipoVector Control Product Testing Unit, Ifakara Health Institute (IHI), Bagamoyo, Tanzania.
Mohammed Ally RashidVector Control Product Testing Unit, Ifakara Health Institute (IHI), Bagamoyo, Tanzania.
Rune BosselmannVegro Aps, Copenhagen, Denmark.
Ole SkovmandMCC47, Montpellier, France.
John BradleyMRC International Statistics and Epidemiology Group, London School of Hygiene and Tropical Medicine (LSHTM), London, UK.
Ifakara Health Institute · TZLondon School of Hygiene & Tropical Medicine · GB

Funding

Medical Research Council MR/R010161/1Medical Research Council MR/T003677/1Medical Research Council MR/T0036771 & EPIDZR44
6 · The paper itself

Abstract

backgroundLong-lasting insecticidal nets (LLINs) have contributed to the reduction of malaria in sub-Saharan Africa, including Tanzania. However, they rely on daily user behaviour and high coverage which is difficult to maintain. Also, insecticide resistance among malaria vector mosquitoes is contributing to reduced efficacy of control tools. To overcome these problems, we propose to evaluate a new tool for house modification, the insecticide-treated eave nets (ITENs) in combination with insecticide-treated window screens (ITWS) incorporated with dual active ingredient (dual AI) for the control of malaria.

methodsFour hundred and fifty (450) households with intact walls, open eaves without screens or nets on the windows in Chalinze district will be eligible and recruited upon written informed consent. The households will be randomly allocated into two arms: one with ITENs and ITWS installed and the other without. Malaria parasite detection using a quantitative polymerase chain reaction (qPCR) will be conducted shortly after the long rain (June/July, 2022) as the primary outcome and shortly after the short rain (January/February, 2022) as the secondary outcome. Other secondary outcomes include clinical malaria cases, and density of malaria vectors and nuisance after the short rain and long rain. In addition, surveys will be conducted in households with ITENs and ITWS to estimate the intervention's cost during installation, adverse effects one month after installation, and presence, fabric integrity and user acceptance six and twelve months after installation. Bioefficacy and chemical content will be evaluated twelve months after installation. DISCUSSION: ITENs and ITWS have been shown in Kenya to reduce indoor mosquito density. However, it is not known if indoor mosquito density reduction translates into reduction of malaria cases. Data from the study will measure the potential public health value of an additional intervention for malaria control at the household level in areas of mosquito insecticide resistance that does not require daily adherence.

trial registrationThe study is registered on ClinicalTrials.gov .

Indexed as

AnophelesInsecticidesInsecticide-Treated BednetsMalariaAnimalsHumansMosquito ControlMosquito VectorsRandomized Controlled Trials as TopicTanzaniaInsecticidesEavesHouse modificationInsecticide-treated netsMalariaMosquitoRandomised controlled trialTanzaniaVector-borne diseasesWindows

Identifiers

PMID35854371
PMCPMC9295261
OpenAlexW4286218327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.