Evidence map›Paper›PMID 35854060›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2022

Comparing patient global impression of severity and patient global impression of change to evaluate test-retest reliability of depression, non-small cell lung cancer, and asthma measures.

Sonya Eremenco, Wen-Hung Chen, Steven I Blum, Elizabeth Nicole Bush, Donald M Bushnell, Kendra DeBusk, Adam Gater, Linda Nelsen, Stephen Joel Coons, PRO Consortium’s Communication Subcommittee

Open access · hybridAbstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Guideline
  2. Determining the minimal important difference of EQ-5D-5 L utility values in CIDP patients using data from a large clinical trial.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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  5. Myelofibrosis symptom assessment form total symptom score version 4.0: measurement properties from the MOMENTUM phase 3 study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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  19. A retrospective comparative cohort study of ultra-pulse COAnnals of translational medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Sonya EremencoCritical Path Institute, 1730 East River Road, Suite 200, Tucson, AZ, USA. seremenco@c-path.org.ORCID http://orcid.org/0000-0003-3956-0235
Wen-Hung ChenGlaxoSmithKline, Collegeville, PA, USA.
Steven I BlumBristol Myers Squibb, Lawrenceville, NJ, USA.
Elizabeth Nicole BushEli Lilly and Company, Indianapolis, IN, USA.
Donald M BushnellEvidera | PPD, Phoenix, AZ, USA.
Kendra DeBuskSeagen Inc, Bothell, WA, USA.
Adam GaterAdelphi Values, Bollington, Cheshire, UK.
Linda NelsenGlaxoSmithKline, Collegeville, PA, USA.
Stephen Joel CoonsCritical Path Institute, 1730 East River Road, Suite 200, Tucson, AZ, USA.ORCID http://orcid.org/0000-0001-7977-5156
PRO Consortium’s Communication Subcommittee
Critical Path Institute · USGlaxoSmithKline (United States) · USAdelphi Group (United Kingdom) · GBBristol-Myers Squibb (United States) · USEli Lilly (United States) · USIthaka Harbors · USSeagen (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeScore reproducibility is an important measurement property of fit-for-purpose patient-reported outcome (PRO) measures. It is commonly assessed via test-retest reliability, and best evaluated with a stable participant sample, which can be challenging to identify in diseases with highly variable symptoms. To provide empirical evidence comparing the retrospective (patient global impression of change [PGIC]) and current state (patient global impression of severity [PGIS]) approaches to identifying a stable subgroup for test-retest analyses, 3 PRO Consortium working groups collected data using both items as anchor measures.

methodsThe PGIS was completed on Day 1 and Day 8 + 3 for the depression and non-small cell lung cancer (NSCLC) studies, and daily for the asthma study and compared between Day 3 and 10. The PGIC was completed on the final day in each study. Scores were compared using an intraclass correlation coefficient (ICC) for participants who reported "no change" between timepoints for each anchor.

resultsICCs using the PGIS "no change" group were higher for depression (0.84 vs. 0.74), nighttime asthma (0.95 vs. 0.53) and daytime asthma (0.86 vs. 0.68) compared to the PGIC "no change" group. ICCs were similar for NSCLC (PGIS: 0.87; PGIC: 0.85).

conclusionWhen considering anchor measures to identify a stable subgroup for test-retest reliability analyses, current state anchors perform better than retrospective anchors. Researchers should carefully consider the type of anchor selected, the time period covered, and should ensure anchor content is consistent with the target measure concept, as well as inclusion of both current and retrospective anchor measures.

Indexed as

AsthmaCarcinoma, Non-Small-Cell LungLung NeoplasmsDepressionHumansQuality of LifeReproducibility of ResultsRetrospective StudiesClinical outcome assessmentPatient-reported outcome measurePGICPGISTest–retest reliability

Identifiers

PMID35854060
PMCPMC9587936
OpenAlexW4286220322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.