Evidence map›Paper›PMID 35853960›Full record

ArticleScientific reports2022

Genomic epidemiology of SARS-CoV-2 in a university outbreak setting and implications for public health planning.

Sema Nickbakhsh, Joseph Hughes, Nicolaos Christofidis, Emily Griffiths, Sharif Shaaban, Jessica Enright, Katherine Smollett, Kyriaki Nomikou, Natasha Palmalux, Lily Tong and 15 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Genome Sequencing in Infectious Disease Outbreaks.Advances in experimental medicine and biology · 2026
    Review
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 20 institutions in 1 country.

Sema Nickbakhsh *Public Health Scotland, Meridian Court, 5 Cadogan Street, Glasgow, G2 6QE, UK. Sema.Nickbakhsh@phs.scot.ORCID 0000-0001-9543-7536
Joseph Hughes *Public Health Scotland, Meridian Court, 5 Cadogan Street, Glasgow, G2 6QE, UK.
Nicolaos ChristofidisPublic Health Scotland, Meridian Court, 5 Cadogan Street, Glasgow, G2 6QE, UK.
Emily GriffithsPublic Health Scotland, Meridian Court, 5 Cadogan Street, Glasgow, G2 6QE, UK.
Sharif ShaabanPublic Health Scotland, Meridian Court, 5 Cadogan Street, Glasgow, G2 6QE, UK.
Jessica EnrightSchool of Computing Science, University of Glasgow, 18 Lilybank Gardens, Glasgow, G12 8RZ, UK.
Katherine SmollettMRC-University of Glasgow Centre for Virus Research, 464 Bearsden Road, Glasgow, G61 1QH, UK.
Kyriaki NomikouMRC-University of Glasgow Centre for Virus Research, 464 Bearsden Road, Glasgow, G61 1QH, UK.
Natasha PalmaluxMRC-University of Glasgow Centre for Virus Research, 464 Bearsden Road, Glasgow, G61 1QH, UK.
Lily TongMRC-University of Glasgow Centre for Virus Research, 464 Bearsden Road, Glasgow, G61 1QH, UK.
Stephen CarmichaelMRC-University of Glasgow Centre for Virus Research, 464 Bearsden Road, Glasgow, G61 1QH, UK.
Vattipally B SreenuMRC-University of Glasgow Centre for Virus Research, 464 Bearsden Road, Glasgow, G61 1QH, UK.ORCID 0000-0001-6673-4697
Richard OrtonMRC-University of Glasgow Centre for Virus Research, 464 Bearsden Road, Glasgow, G61 1QH, UK.ORCID 0000-0002-3389-4325
Emily J GoldsteinWest of Scotland Specialist Virology Centre, NHS Greater Glasgow and Clyde, Glasgow Royal Infirmary, New Lister Building, Glasgow, G31 2ER, UK.
Rachael M TombWest of Scotland Specialist Virology Centre, NHS Greater Glasgow and Clyde, Glasgow Royal Infirmary, New Lister Building, Glasgow, G31 2ER, UK.
COVID-19 Genomics UK (COG-UK) Consortium
Kate TempletonRoyal Infirmary of Edinburgh, NHS Lothian, 51 Little France Crescent, Edinburgh, EH16 4SA, UK.
Rory N GunsonWest of Scotland Specialist Virology Centre, NHS Greater Glasgow and Clyde, Glasgow Royal Infirmary, New Lister Building, Glasgow, G31 2ER, UK.
Ana da Silva FilipeMRC-University of Glasgow Centre for Virus Research, 464 Bearsden Road, Glasgow, G61 1QH, UK.
Catriona MilosevicNHS Greater Glasgow and Clyde, Gartnavel General Hospital, 1055 Great Western Road, Glasgow, G12 0XH, UK.
Emma ThomsonPublic Health Scotland, Meridian Court, 5 Cadogan Street, Glasgow, G2 6QE, UK.ORCID 0000-0003-1482-0889
David L RobertsonPublic Health Scotland, Meridian Court, 5 Cadogan Street, Glasgow, G2 6QE, UK.ORCID 0000-0001-6338-0221
Matthew T G HoldenPublic Health Scotland, Meridian Court, 5 Cadogan Street, Glasgow, G2 6QE, UK.
Christopher J R IllingworthMRC-University of Glasgow Centre for Virus Research, 464 Bearsden Road, Glasgow, G61 1QH, UK. Christopher.Illingworth@glasgow.ac.uk.
Alison Smith-PalmerPublic Health Scotland, Meridian Court, 5 Cadogan Street, Glasgow, G2 6QE, UK.
Wellcome Sanger Institute · GBUniversity of Cambridge · GBPublic Health Wales · GBPublic Health England · GBMRC University of Glasgow Centre for Virus Research · GBUniversity of Sheffield · GBUniversity of Birmingham · GBUniversity of Liverpool · GBQueen's University Belfast · GBUniversity College London Hospitals NHS Foundation Trust · GBUniversity of Nottingham · GBPublic Health Scotland · GBQuadram Institute · GBUniversity Hospitals Sussex NHS Foundation Trust · GBUniversity of Edinburgh · GBCardiff University · GBUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Oxford · GBGuy's and St Thomas' NHS Foundation Trust · GBNHS Greater Glasgow and Clyde · GB

Funding

Department of Health MC_PC_19027Medical Research Council MC_PC_19026Medical Research Council MC_PC_19027Medical Research Council MC_UU_12014/12Medical Research Council MC_UU_12018/12Medical Research Council MR/L015080/1Medical Research Council MR/T030062/1
6 · The paper itself

Abstract

Whole genome sequencing of SARS-CoV-2 has occurred at an unprecedented scale, and can be exploited for characterising outbreak risks at the fine-scale needed to inform control strategies. One setting at continued risk of COVID-19 outbreaks are higher education institutions, associated with student movements at the start of term, close living conditions within residential halls, and high social contact rates. Here we analysed SARS-CoV-2 whole genome sequences in combination with epidemiological data to investigate a large cluster of student cases associated with University of Glasgow accommodation in autumn 2020, Scotland. We identified 519 student cases of SARS-CoV-2 infection associated with this large cluster through contact tracing data, with 30% sequencing coverage for further analysis. We estimated at least 11 independent introductions of SARS-CoV-2 into the student population, with four comprising the majority of detected cases and consistent with separate outbreaks. These four outbreaks were curtailed within a week following implementation of control measures. The impact of student infections on the local community was short-term despite an underlying increase in community infections. Our study highlights the need for context-specific information in the formation of public health policy for higher educational settings.

Indexed as

COVID-19SARS-CoV-2Disease OutbreaksGenomicsHealth PlanningHumansUnited StatesUniversities

Identifiers

PMID35853960
PMCPMC9296497
OpenAlexW4285794899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.