ArticleEvidence-based mental health2022
From living systematic reviews to meta-analytical research domains.
Article in Evidence-based mental health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Pooled it
- Self-reports vs clinician ratings of efficacies of psychotherapies for depression: a meta-analysis of randomized trials.Epidemiology and psychiatric sciences · 2025Pooled it
- Psychotherapies for Generalized Anxiety Disorder in Adults: A Systematic Review and Network Meta-Analysis of Randomized Clinical Trials.JAMA psychiatry · 2024Pooled it
- Comparative Effectiveness of Individual, Group, Family and Combined Therapy Formats on Suicidality: A Meta-Analysis.Clinical psychology & psychotherapyPooled it
- Big data and psychiatry: advances, constraints and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- Article
- Innovations to improve outcomes and uptake of psychotherapies for mental disorders: a state-of-the-art review.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026Article
- Effectiveness and acceptability of exercise treatments for adults with anxiety disorders: a systematic review and network meta-analysis.BMJ open sport & exercise medicine · 2026Article
- Effectiveness of digital interventions for eight mental disorders: A meta-analytic synthesis.Internet interventions · 2025Review
- metaConvert: an automatic suite for estimation of 11 different effect size measures and flexible conversion across them.Research synthesis methods · 2025Article
- Towards person-centered care in global mental health: implications for meta-analyses and clinical trials.Epidemiology and psychiatric sciences · 2025Article
- Comparative efficacy and acceptability of psychosocial interventions for PTSD, depression, and anxiety in asylum seekers, refugees, and other migrant populations: a systematic review and network meta-analysis of randomised controlled studies.The Lancet regional health. Europe · 2025Article
- Standardized effect sizes are far from "Standardized": A primer and empirical illustration in depression psychotherapy meta-analyses.PLOS mental health · 2025Article
- A living critical interpretive synthesis to yield a framework on the production and dissemination of living evidence syntheses for decision-making.Implementation science : IS · 2024Review
- Mapping the evidence on psychosocial interventions for migrant populations: Descriptive analysis of a living database of randomized studies.Global mental health (Cambridge, England) · 2024Review
- Article
- Evidence-based yet still challenging! Research on physical activity in old age.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2023Article
- What I stand for asBMJ mental health · 2023Article
- Data sharing and re-use in the traumatic stress field: An international survey of trauma researchers.European journal of psychotraumatology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Because of the rapidly increasing number of randomised controlled trials (RCTs) and meta-analyses in many fields, there is an urgent need to step up from meta-analyses to higher levels of aggregation of outcomes of RCTs. Network meta-analyses and umbrella reviews allow higher levels of aggregation of RCT outcomes, but cannot adequately cover the evidence for a whole field. The 'Meta-Analytic Research Domain' (MARD) may be a new methodology to aggregate RCT data of a whole field. A MARD is a living systematic review of a research domain that cannot be covered by one PICO. For example, a MARD of psychotherapy for depression covers all RCTs comparing the effects of all types of psychotherapy to control conditions, to each other, to pharmacotherapy and combined treatment. It also covers all RCTs comparing treatment formats, the effects in different target groups, subtypes of depression and secondary outcomes. Although the time and resources needed to build a MARD are considerable, they offer many advantages, including a comprehensive and consistent overview of a research field and important meta-analytic studies that cannot be conducted with conventional methods. MARDs are a promising method to step up the aggregation of RCTs to a next level and it is highly relevant to work out the methods of this approach in a more detailed way.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.