Evidence map›Paper›PMID 35853718›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022

Dopamine Modulates Adaptive Forgetting in Medial Prefrontal Cortex.

Francisco Tomás Gallo, María Belén Zanoni Saad, Azul Silva, Juan Facundo Morici, Magdalena Miranda, Michael C Anderson, Noelia V Weisstaub, Pedro Bekinschtein

Open access · hybridAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Striatal Gradient in Value-Decay Explains Regional Differences in Dopamine Patterns and Reinforcement Learning Computations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  3. Review
  4. Review
  5. Article
  6. Prefrontal-hippocampal interactions supporting the extinction of emotional memories: the retrieval stopping model.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Francisco Tomás GalloLaboratorio de Memoria y Cognición Molecular, Instituto de Neurociencia Cognitiva y Traslacional, Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)-Fundación INECO-Universidad Favaloro, 1071 Ciudad Autónoma de Buenos Aires, Argentina.ORCID https://orcid.org/0000-0003-1393-0218
María Belén Zanoni SaadLaboratorio de Memoria y Cognición Molecular, Instituto de Neurociencia Cognitiva y Traslacional, Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)-Fundación INECO-Universidad Favaloro, 1071 Ciudad Autónoma de Buenos Aires, Argentina.
Azul SilvaGrupo de Neurociencia de Sistemas, Instituto de Fisiología y Biofísica "Houssay" (IFIBIO "Houssay"), Universidad de Buenos Aires, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), C1121ABG Ciudad Autónoma de Buenos Aires, Argentina.
Juan Facundo MoriciLaboratorio de Memoria y Cognición Molecular, Instituto de Neurociencia Cognitiva y Traslacional, Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)-Fundación INECO-Universidad Favaloro, 1071 Ciudad Autónoma de Buenos Aires, Argentina.ORCID https://orcid.org/0000-0002-5207-0428
Magdalena MirandaLaboratorio de Memoria y Cognición Molecular, Instituto de Neurociencia Cognitiva y Traslacional, Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)-Fundación INECO-Universidad Favaloro, 1071 Ciudad Autónoma de Buenos Aires, Argentina.
Michael C AndersonMRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge CB2 7EF, United Kingdom.
Noelia V WeisstaubLaboratorio de Memoria y Cognición Molecular, Instituto de Neurociencia Cognitiva y Traslacional, Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)-Fundación INECO-Universidad Favaloro, 1071 Ciudad Autónoma de Buenos Aires, Argentina.
Pedro BekinschteinLaboratorio de Memoria y Cognición Molecular, Instituto de Neurociencia Cognitiva y Traslacional, Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET)-Fundación INECO-Universidad Favaloro, 1071 Ciudad Autónoma de Buenos Aires, Argentina pbekinschtein@favaloro.edu.ar.ORCID https://orcid.org/0000-0002-0004-9619
Consejo Nacional de Investigaciones Científicas y Técnicas · ARMRC Cognition and Brain Sciences Unit · GB

Funding

Medical Research Council MC_UU_00005/1
6 · The paper itself

Abstract

Active forgetting occurs in many species, but how behavioral control mechanisms influence which memories are forgotten remains unknown. We previously found that when rats need to retrieve a memory to guide exploration, it reduces later retention of other competing memories encoded in that environment. As with humans, this retrieval-induced forgetting relies on prefrontal control processes. Dopaminergic input to the prefrontal cortex is important for executive functions and cognitive flexibility. We found that, in a similar way, retrieval-induced forgetting of competing memories in male rats requires prefrontal dopamine signaling through D

Indexed as

DopamineMental RecallAnimalsHumansMalePrefrontal CortexRatsReceptors, Dopamine D1Ventral Tegmental AreaDopamineReceptors, Dopamine D1active forgettingD1 receptorsinhibitory controlmedial prefrontal cortexretrieval-induced forgetting

Identifiers

PMID35853718
PMCPMC9410750
OpenAlexW4285793724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.