Evidence map›Paper›PMID 35853600›Full record

Trial reportAcademic pediatrics

Performance Feedback for Human Papillomavirus Vaccination: A Randomized Trial From the American Academy of Pediatrics Pediatric Research in Office Settings Research Network.

Alexander G Fiks, Alisa J Stephens-Shields, Mary Kate Kelly, Russell Localio, Chloe Hannan, Robert W Grundmeier, Laura P Shone, Jennifer Steffes, Margaret Wright, Abigail Breck and 6 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Academic pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Alexander G FiksCenter for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia (AG Fiks, MK Kelly, C Hannan, and RW Grundmeier), Philadelphia, Pa; Pediatric Research in Office Settings, American Academy of Pediatrics (AG Fiks, LP Shone, J Steffes, G McFarland, and DE Abney), Itasca, Ill. Electronic address: fiks@chop.edu.
Alisa J Stephens-ShieldsDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania (AJ Stephens-Shields and R Localio), Philadelphia, Pa.
Mary Kate KellyCenter for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia (AG Fiks, MK Kelly, C Hannan, and RW Grundmeier), Philadelphia, Pa.
Russell LocalioDepartment of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania (AJ Stephens-Shields and R Localio), Philadelphia, Pa.
Chloe HannanCenter for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia (AG Fiks, MK Kelly, C Hannan, and RW Grundmeier), Philadelphia, Pa.
Robert W GrundmeierCenter for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia (AG Fiks, MK Kelly, C Hannan, and RW Grundmeier), Philadelphia, Pa; Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia (RW Grundmeier), Philadelphia, Pa.
Laura P ShonePediatric Research in Office Settings, American Academy of Pediatrics (AG Fiks, LP Shone, J Steffes, G McFarland, and DE Abney), Itasca, Ill; Primary Care Research, American Academy of Pediatrics (LP Shone and J Steffes), Itasca, Ill.
Jennifer SteffesPediatric Research in Office Settings, American Academy of Pediatrics (AG Fiks, LP Shone, J Steffes, G McFarland, and DE Abney), Itasca, Ill; Primary Care Research, American Academy of Pediatrics (LP Shone and J Steffes), Itasca, Ill.
Margaret WrightCancer Center, University of Illinois (M Wright), Chicago, Ill.
Abigail BreckDepartment of Pediatrics, University of California Los Angeles Mattel Children's Hospital (A Breck, C Albertin, and PG Szilagyi), Los Angeles, Calif.
Cynthia M RandDepartment of Pediatrics, University of Rochester (CM Rand), Rochester, NY.
Christina AlbertinDepartment of Pediatrics, University of California Los Angeles Mattel Children's Hospital (A Breck, C Albertin, and PG Szilagyi), Los Angeles, Calif.
Sharon G HumistonDepartment of Pediatrics, Children's Mercy Hospital (SG Humiston), Kansas City, Mo.
Greta McFarlandPediatric Research in Office Settings, American Academy of Pediatrics (AG Fiks, LP Shone, J Steffes, G McFarland, and DE Abney), Itasca, Ill.
Dianna E AbneyPediatric Research in Office Settings, American Academy of Pediatrics (AG Fiks, LP Shone, J Steffes, G McFarland, and DE Abney), Itasca, Ill.
Peter G SzilagyiDepartment of Pediatrics, University of California Los Angeles Mattel Children's Hospital (A Breck, C Albertin, and PG Szilagyi), Los Angeles, Calif.

Funding

Improving HPV Vaccination Delivery in Pediatric Primary Care: The STOP-HPV TrialR01CA202261 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FIKS, ALEXANDER GABRIEL, SZILAGYI, PETER G · 2017 to 2022
$3.1M
NCI NIH HHS R01 CA202261
6 · The paper itself

Abstract

objectiveTo test the hypothesis that a feedback-based intervention would reduce human papillomavirus (HPV) vaccine missed opportunities.

methodsIn a longitudinal cluster randomized controlled trial of 48 pediatric primary care practices, we allocated half the practices to receive a sequential, multicomponent intervention phased over consecutive periods. In a prior trial (period 1), communication skills training reduced missed opportunities for the initial HPV vaccine dose at well visits but not at acute/chronic visits. The current trial (period 2) evaluated the added value of performance feedback to clinicians after communication training. Performance feedback consisted of an introductory training module, weekly electronic "Quick Tips," and 3 individualized performance feedback reports to clinicians. We fit logistic regression models for the primary outcome of HPV vaccination missed opportunities using generalized estimating equations with independence working correlation, accounting for clustering at the practice level.

resultsPerformance feedback resulted in a 3.4 (95% confidence interval [CI]: -6.8, 0.0) percentage point greater reduction in missed HPV vaccine opportunities for the intervention versus control group during acute/chronic visits for subsequent HPV vaccinations (dose 2 or 3). However, during well visits for HPV vaccination dose #1, intervention practices increased missed opportunities (worsened) by 4.2 (95% CI: 1.0, 7.4) percentage points more than control practices, reducing the prior period 1 improvements and blunting the overall effect of performance feedback. We did not observe differences for the other visit/dose categories.

conclusionsPerformance feedback improved HPV vaccination for one subset of visits (acute/chronic, subsequent HPV vaccinations due), but not for well visits.

Indexed as

Papillomavirus InfectionsPapillomavirus VaccinesChildFeedbackHuman Papillomavirus VirusesHumansUnited StatesVaccinationPapillomavirus Vaccineshuman papillomavirusmissed opportunitiesPediatric Research in Office Settingsvaccination

Identifiers

PMID35853600
PMCPMC13329936

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.