Evidence map›Paper›PMID 35853192›Full record

ArticleJCO global oncology2022

Cancer Medicines: What Is Essential and Affordable in India?

Manju Sengar, Adam Fundytus, Wilma Hopman, C S Pramesh, Venkatraman Radhakrishnan, Prasanth Ganesan, Aju Mathew, Dorothy Lombe, Matthew Jalink, Bishal Gyawali and 7 more

Open access · goldAbstract read
In one paragraph

Article in JCO global oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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  9. A National Cancer Grid pooled procurement initiative, India.Bulletin of the World Health Organization · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 6 countries.

Manju SengarDepartment of Medical Oncology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.ORCID 0000-0002-3509-5682
Adam FundytusDivision of Cancer Care and Epidemiology, Queen's University Cancer Research Institute, Kingston, Canada.ORCID 0000-0001-9119-9710
Wilma HopmanDepartment of Public Health Sciences, Queen's University, Kingston, Canada.ORCID 0000-0002-3023-0080
C S PrameshDepartment of Surgical Oncology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, India.ORCID 0000-0002-3635-0083
Venkatraman RadhakrishnanDepartment of Medical Oncology, Cancer Institute (W.I.A.), Chennai, India.ORCID 0000-0002-7557-5816
Prasanth GanesanDepartment of Medical Oncology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.ORCID 0000-0003-2762-6591
Aju MathewMalankara Orthodox Syrian Church Medical College, Kolenchery, India.ORCID 0000-0002-5482-5708
Dorothy LombeCancer Diseases Hospital, Lusaka, Zambia.ORCID 0000-0002-5083-1801
Matthew JalinkDivision of Cancer Care and Epidemiology, Queen's University Cancer Research Institute, Kingston, Canada.ORCID 0000-0002-2269-8521
Bishal GyawaliDivision of Cancer Care and Epidemiology, Queen's University Cancer Research Institute, Kingston, Canada.ORCID 0000-0001-7444-8594
Dario TrapaniDivision of Early Drug Development for Innovative Therapies, European Institute of Oncology IRCCS, Milan, Italy.
Felipe RoitbergDepartment of Noncommunicable Diseases, World Health Organization, Geneva, Switzerland.ORCID 0000-0003-2546-543X
Elisabeth G E De VriesDepartment of Medical Oncology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Lorenzo MojaDepartment of Health Products Policy and Standards, World Health Organization, Geneva, Switzerland.ORCID 0000-0001-6680-6507
André IlbawiDepartment of Health Products Policy and Standards, World Health Organization, Geneva, Switzerland.ORCID 0000-0002-4751-6595
Richard SullivanInstitute of Cancer Policy, King's College London, London, United Kingdom.ORCID 0000-0002-6435-1825
Christopher M BoothDivision of Cancer Care and Epidemiology, Queen's University Cancer Research Institute, Kingston, Canada.ORCID 0000-0002-1353-3653
Queen's University · CAWorld Health Organization · CHHomi Bhabha National Institute · INCancer Institute (WIA) · INEuropean Institute of Oncology · ITJawaharlal Institute of Post Graduate Medical Education and Research · INKing's College London · GBMalankara Orthodox Syrian Church Medical College Hospital · INUniversity Medical Center Groningen · NL

Funding

Medical Research Council MR/W023903/1World Health Organization 001
6 · The paper itself

Abstract

purposeThe WHO essential medicines list (EML) guides selection of drugs for national formularies. Here, we evaluate which medicines are considered highest priority by Indian oncologists and the extent to which they are available in routine practice.

methodsThis is a secondary analysis of an electronic survey developed by the WHO EML Cancer Medicine Working Group. The survey was distributed globally using a hierarchical snowball method to physicians who prescribe systemic anticancer therapy. The survey captured the 10 medicines oncologists considered highest priority for population health and their availability in routine practice.

resultsThe global study cohort included 948 respondents from 82 countries; 98 were from India and 67 were from other low- and middle-income countries. Compared with other low- and middle-income countries, the Indian cohort was more likely to be medical oncologist (70%

conclusionMost high-priority cancer medicines identified by Indian oncologists are generic chemotherapy agents that provide substantial improvements in survival and are already included in WHO EML. Access to these treatments remains limited by major financial burdens experienced by patients. This is particularly acute within the private health system. Strategies are urgently needed to ensure that high-quality cancer care is affordable and accessible to all patients in India.

Indexed as

Antineoplastic AgentsDrugs, EssentialNeoplasmsCosts and Cost AnalysisHumansIndiaAntineoplastic AgentsDrugs, Essential

Identifiers

PMID35853192
PMCPMC9812506
OpenAlexW4286255302

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.