Evidence map›Paper›PMID 35852719›Full record

ArticleSurgical case reports2022

Acute intestinal necrosis due to multiple thrombosis in COVID-19 patient. Report of a case.

Hirotsugu Morioka, Michitoshi Goto, Haruka Tanaka, Hirotaka Momose, Kazuyoshi Fujino, Toshiaki Hagiwara, Jun Aoki, Michihiro Orihata, Kotaro Kaneko

Open access · goldAbstract read
In one paragraph

Article in Surgical case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hirotsugu MoriokaDepartment of Surgery, Tokyo Rinkai Hospital, 1-4-2 Rinkai-Cho, Edogawa-Ku, Tokyo, 134-0086, Japan. hirotsugu0419@yahoo.co.jp.
Michitoshi GotoDepartment of Surgery, Tokyo Rinkai Hospital, 1-4-2 Rinkai-Cho, Edogawa-Ku, Tokyo, 134-0086, Japan.
Haruka TanakaDepartment of Surgery, Tokyo Rinkai Hospital, 1-4-2 Rinkai-Cho, Edogawa-Ku, Tokyo, 134-0086, Japan.
Hirotaka MomoseDepartment of Surgery, Tokyo Rinkai Hospital, 1-4-2 Rinkai-Cho, Edogawa-Ku, Tokyo, 134-0086, Japan.
Kazuyoshi FujinoDepartment of Surgery, Tokyo Rinkai Hospital, 1-4-2 Rinkai-Cho, Edogawa-Ku, Tokyo, 134-0086, Japan.
Toshiaki HagiwaraDepartment of Surgery, Tokyo Rinkai Hospital, 1-4-2 Rinkai-Cho, Edogawa-Ku, Tokyo, 134-0086, Japan.
Jun AokiDepartment of Surgery, Tokyo Rinkai Hospital, 1-4-2 Rinkai-Cho, Edogawa-Ku, Tokyo, 134-0086, Japan.
Michihiro OrihataDepartment of Surgery, Tokyo Rinkai Hospital, 1-4-2 Rinkai-Cho, Edogawa-Ku, Tokyo, 134-0086, Japan.
Kotaro KanekoDepartment of Pediatric Surgery, Juntendo University, Tokyo, Japan.
Tokyo Rinkai Hospital · JPJuntendo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile thrombosis is a well-known complication of coronavirus disease 2019 (COVID-19) infection, reports on intestinal necrosis due to intestinal ischemia caused by thrombosis are extremely rare. We herein report a case of intestinal necrosis due to multiple thrombosis in a COVID-19 patient. CASE PRESENTATION: The patient was a 64-year-old man. He was admitted to hospital after being diagnosed with COVID-19, the severity was classified as moderate II. Nasal High Flow™ management was conducted along with treatment with tocilizumab, remdesivir, and dexamethasone. Heparin was also administered due to high D-dimer values. As abdominal pain appeared from the 6th day of hospitalization, contrast-enhanced CT was performed, which confirmed multiple thrombosis in the aorta. However, no obvious intestinal ischemia was found. On the 10th day of hospitalization, the patient's abdominal pain was exacerbated. Upon re-evaluation by CT, he was diagnosed with perforative peritonitis due to ileal ischemic necrosis and emergency surgery was performed. Intraoperative examination revealed perforation due to necrosis at multiple sites in the ileum; thus, partial ileectomy was carried out. Pathological findings also revealed discontinuous multiple intestinal necrosis due to the frequent occurrence of thrombosis. Following surgery, the patient recuperated and was discharged after ventilator management and multimodal therapy at the ICU.

conclusionsThrombosis due to COVID-19 complications is rare in the intestinal tract, but also occur. Its initial symptoms might not be captured by CT images, therefore caution is required.

Indexed as

COVID-19Intestinal ischemiaIntestinal necrosisThrombosis

Identifiers

PMID35852719
PMCPMC9295081
OpenAlexW4285793644

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.