Evidence map›Paper›PMID 35852701›Full record

ArticleResearch on child and adolescent psychopathology2022

Childhood behavioral inhibition and overcontrol: Relationships with cognitive functioning, error monitoring, anxiety and obsessive-compulsive symptoms.

Kirsten Gilbert, Ella Sudit, Nathan A Fox, Deanna M Barch, Joan L Luby

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Research on child and adolescent psychopathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kirsten GilbertDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA. gilbertk@wustl.edu.ORCID 0000-0001-9367-6621
Ella SuditDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0002-3449-6185
Nathan A FoxDepartment of Human Development and Quantitative Methodology, University of Maryland, College Park, Maryland, USA.ORCID 0000-0003-4452-4503
Deanna M BarchDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0003-1693-8506
Joan L LubyDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.ORCID 0000-0001-5352-1721
Washington University in St. Louis · USUniversity of Maryland, College Park · US

Funding

Heightened Performance Monitoring and Overcontrol: Neural Markers and Caregiving Processes in Developmental Risk TrajectoriesK23MH115074 · NIMH · WASHINGTON UNIVERSITY · PI GILBERT, KIRSTEN · 2017 to 2021
$821k
NIMH NIH HHS K23 MH115074
6 · The paper itself

Abstract

Anxiety and obsessive-compulsive disorders are common childhood psychiatric disorders. Behavioral inhibition (BI) is a widely studied risk factor for anxiety. Less is known about overcontrol, a related behavioral phenotype characterized by concern for errors, perfectionism, and inflexibility and also associated with anxiety and obsessive-compulsive disorder. Both BI and overcontrol show associations with aberrant cognitive control and neural error responding (via the error-related negativity; ERN) yet it is unknown whether each imparts differential risk. Understanding whether overcontrol demonstrates independent associations from BI with cognitive functioning, neural error monitoring, and childhood anxiety and obsessive-compulsive presentations could aid in identifying a novel mechanistic treatment target. We assessed BI, overcontrol, cognitive functioning and psychopathology in a cross-sectional sample of 5-6 year old children (N = 126). Children completed an electroencephalogram (EEG) to assess the ERN. Overcontrol was associated with worse cognitive shifting, worse inhibitory control and higher anxiety and obsessive-compulsive symptoms, beyond BI. BI was associated with worse cognitive shifting, better inhibitory control and higher anxiety symptoms, beyond overcontrol. When assessed simultaneously, only overcontrol demonstrated a significant relationship with a blunted ERN. Moreover, overcontrol mediated (cross-sectionally) the well-established relationship between ERN and anxiety and obsessive-compulsive symptoms. BI and overcontrol impart differential risk for child cognitive functioning and anxiety while overcontrol demonstrates additional risk for aberrant neural error monitoring, anxiety and obsessive-compulsive presentations. Overcontrol may also be a mechanistic pathway between the ERN and transdiagnostic anxiety and obsessive-compulsive symptoms. Overcontrol may be a target warranted for early-childhood intervention in anxiety and OCD.

Indexed as

Evoked PotentialsObsessive-Compulsive DisorderAnxietyChildCognitionCross-Sectional StudiesHumansBehavioral inhibitionError-related negativityOCDOvercontrolPediatric anxietyPerformance monitoring

Identifiers

PMID35852701
PMCPMC9906714
OpenAlexW4285793636

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.