Evidence map›Paper›PMID 35852684›Full record

Trial reportBulletin of experimental biology and medicine2022

Effect of Repetitive Transcranial Magnetic Stimulation on Serum Levels of Steroid Adrenal Hormones in Parkinson's Disease: Sex Differences.

L I Aftanas, S Ya Zhanaeva, E L Al'perina, G V Idova, M M Gevorgyan, S S Dzemidovich, K I Kulikova

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Bulletin of experimental biology and medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Clinical neurophysiology in the treatment of movement disorders: IFCN handbook chapter.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2024
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

L I AftanasResearch Institute of Neurosciences and Medicine, Novosibirsk, Russia.
S Ya ZhanaevaResearch Institute of Neurosciences and Medicine, Novosibirsk, Russia. s.zhanaeva@physiol.ru.
E L Al'perinaResearch Institute of Neurosciences and Medicine, Novosibirsk, Russia.
G V IdovaResearch Institute of Neurosciences and Medicine, Novosibirsk, Russia.
M M GevorgyanResearch Institute of Neurosciences and Medicine, Novosibirsk, Russia.
S S DzemidovichResearch Institute of Neurosciences and Medicine, Novosibirsk, Russia.
K I KulikovaResearch Institute of Neurosciences and Medicine, Novosibirsk, Russia.
Neuroscience Institute · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a parallel placebo-controlled study, we examined the effect of repetitive transcranial magnetic stimulation (rTMS) on serum concentrations of cortisol and dehydroepiandrosteron sulfate (DHEAS), and their relationships with clinical symptoms in men and women with Parkinson's disease. A 20-day course of real rTMS reduced the UPDRS and UPDRS III scores in patients with Parkinson's disease in comparison with the basal parameters (before rTMS), regardless of their sex. The level of cortisol did not change in men and women; at the same time, the content of DHEAS in men increased and before rTMS negatively correlated with the UPDRS scores. Sham rTMS had no effects on clinical parameters or hormonal levels. Possible mechanisms of sex-dependent differences in the effect of rTMS on the level of the neurosteroid hormone DHEAS are discussed.

Indexed as

Parkinson DiseaseTranscranial Magnetic StimulationFemaleHumansHydrocortisoneMaleSex CharacteristicsSteroidsTreatment OutcomeHydrocortisoneSteroidscortisoldehydroepiandrosterone sulfate (DHEAS)Parkinson’s diseaserepetitive transcranial magnetic stimulation (rTMS)sex differences

Identifiers

PMID35852684
OpenAlexW4285797557

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.