Evidence map›Paper›PMID 35852369›Full record

ArticleAntimicrobial agents and chemotherapy2022

Evidence of Fluconazole-Resistant Candida parapsilosis Genotypes Spreading across Hospitals Located in Madrid, Spain and Harboring the Y132F ERG11p Substitution.

Judith Díaz-García, Ana Gómez, Luis Alcalá, Elena Reigadas, Carlos Sánchez-Carrillo, Ana Pérez-Ayala, Elia Gómez-García de la Pedrosa, Fernando González-Romo, Paloma Merino-Amador, María Soledad Cuétara and 12 more

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Detection of Fluconazole Resistance inJournal of fungi (Basel, Switzerland) · 2025
    Article
  5. Review
  6. Clinical impact of fluconazole-resistantFuture microbiology · 2025
    Review
  7. Article
  8. Resistance to Azoles inJournal of fungi (Basel, Switzerland) · 2025
    Article
  9. Article
  10. Threats from theMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  11. Follow the Path: Unveiling an Azole ResistantJournal of fungi (Basel, Switzerland) · 2024
    Article
  12. Article
  13. Article
  14. Analysis of clinicalAntimicrobial agents and chemotherapy · 2024
    Article
  15. Frontiers in cellular and infection microbiology · 2024
    Article
  16. Candida parapsilosis complex in the clinical setting.Nature reviews. Microbiology · 2024
    Review
  17. Article
  18. Analysis of clinicalbioRxiv : the preprint server for biology · 2023
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 13 institutions in 1 country.

Judith Díaz-GarcíaClinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañóngrid.410526.4, Madrid, Spain.ORCID 0000-0001-7216-8281
Ana GómezClinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañóngrid.410526.4, Madrid, Spain.ORCID 0000-0001-8169-4005
Luis AlcaláClinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañóngrid.410526.4, Madrid, Spain.
Elena ReigadasClinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañóngrid.410526.4, Madrid, Spain.ORCID 0000-0003-0609-1305
Carlos Sánchez-CarrilloClinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañóngrid.410526.4, Madrid, Spain.
Ana Pérez-AyalaHospital Universitario 12 de Octubre, Madrid, Spain.ORCID 0000-0001-6426-6279
Elia Gómez-García de la PedrosaHospital Universitario Ramón y Cajal, Madrid, Spain.ORCID 0000-0002-0986-3940
Fernando González-RomoHospital Universitario Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos IdISSC, Madrid, Spain.ORCID 0000-0003-0607-0790
Paloma Merino-AmadorHospital Universitario Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos IdISSC, Madrid, Spain.ORCID 0000-0003-3524-9415
María Soledad CuétaraHospital Universitario Severo Ochoagrid.411361.0, Leganés, Spain.
Coral García-EstebanHospital Universitario de Getafe, Getafe, Spain.
Inmaculada Quiles-MeleroHospital Universitario La Pazgrid.81821.32, Madrid, Spain.ORCID 0000-0001-5268-2902
Nelly Daniela ZuritaHospital Universitario de La Princesa, Madrid, Spain.
María Muñoz-AlgarraHospital Universitario Puerta de Hierro, Majadahonda, Spain.
Isabel Sánchez-RomeroHospital Universitario Puerta de Hierro, Majadahonda, Spain.
María Teresa Durán-ValleHospital Universitario de Móstoles, Móstoles, Spain.
Aída Sánchez-GarcíaLaboratorio Central de la CAM - URSalud, Hospital Infanta Sofía, San Sebastián de los Reyes, Spain.
Eva AlcocebaClinical Microbiology Department, Hospital Universitari Son Espases, Palma de Mallorca, Spain.
Patricia MuñozClinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañóngrid.410526.4, Madrid, Spain.ORCID 0000-0001-5706-5583
Pilar Escribano *Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañóngrid.410526.4, Madrid, Spain.ORCID 0000-0001-6254-4570
Jesús Guinea *Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañóngrid.410526.4, Madrid, Spain.ORCID 0000-0002-7901-8355
CANDIMAD study group
Hospital General Universitario Gregorio Marañón · ESHospital Universitario Puerta de Hierro Majadahonda · ESInstituto de Investigación Sanitaria del Hospital Clínico San Carlos · ESHospital Universitario 12 De Octubre · ESHospital Universitario de Getafe · ESHospital Universitario de La Princesa · ESHospital Universitario de Móstoles · ESHospital Universitario Infanta Sofía · ESHospital Universitario La Paz · ESHospital Universitario Ramón y Cajal · ESHospital Universitario Severo Ochoa · ESHospital Universitario Son Espases · ESUniversidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have been monitoring the antifungal resistance in Candida parapsilosis isolates collected from inpatients at Madrid metropolitan area hospitals for the last 3 years. The study aimed to elucidate the presence of fluconazole-resistant C. parapsilosis genotypes in Madrid. From January 2019 to December 2021, a total of 354 C. parapsilosis isolates (

Indexed as

Candida parapsilosisFluconazoleAntifungal AgentsDrug Resistance, FungalGenotypeHospitalsHumansMicrobial Sensitivity TestsSpainAntifungal AgentsFluconazoleC. parapsilosisfluconazole resistanceG458Smicrosatellite genotypingY132F

Identifiers

PMID35852369
PMCPMC9380585
OpenAlexW4286219267

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.