Evidence map›Paper›PMID 35852368›Full record

ArticleAntimicrobial agents and chemotherapy2022

The Antifungal and Anti-Pneumocystis Activities of the Novel Compound A3IS (Mycosinate).

Nathan P Wiederhold, Thomas F Patterson, Sandra Rebholz, Connell W C Boal, Monika Ehrensberger, Ryan Boyle, Melanie T Cushion

Erratum issuedOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nathan P WiederholdDepartment of Pathology and Laboratory Medicine, The University of Texas Health Science Center, San Antonio, Texas, USA.
Thomas F PattersonDepartment of Medicine, The University of Texas Health Science Center, San Antonio, Texas, USA.
Sandra RebholzDepartment of Internal Medicine, University of Cincinnatigrid.24827.3b College of Medicine, Cincinnati, Ohio, USA.
Connell W C BoalNektr Technologies Ltd., Finisklin Business Park, Sligo, Ireland.
Monika EhrensbergerNektr Technologies Ltd., Finisklin Business Park, Sligo, Ireland.
Ryan BoyleNektr Technologies Ltd., Finisklin Business Park, Sligo, Ireland.
Melanie T CushionDepartment of Internal Medicine, University of Cincinnatigrid.24827.3b College of Medicine, Cincinnati, Ohio, USA.ORCID 0000-0001-6621-2784
The University of Texas Health Science Center at San Antonio · USVeterans Health Administration · US

Funding

BLR&D Research Career Scientist Award ApplicationIK6BX005232 · VA · CINCINNATI VA MEDICAL CENTER RESEARCH · PI Melanie T Cushion · 2020 to 2026
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METHOD OF PROGNOSIS FOR PCP IN PATIENTS WITH AIDSZ01CL000022 · CLC · CLINICAL CENTER · PI SHELHAMER, J H · 1987 to 1987
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BLRD VA IK6 BX005232CLC NIH HHS 75N90019D00022HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) 75N93019D00022/75N93021F00001ORFDO NIH HHS 75N99019D00022
6 · The paper itself

Abstract

A3IS (Mycosinate) is a synthetic product which only contains ingredients found naturally within honey. A3IS is a broad-spectrum antimicrobial product which produces a sustained release of hydrogen peroxide at low but therapeutic levels. The product elicits this release through an enzymatic reaction between glucose oxidase and the substrate glucose once the product is hydrated. As medical uses for different honeys are being re-evaluated, the purpose of this study was to evaluate the

Indexed as

PneumocystisPneumonia, PneumocystisAntifungal AgentsFluconazoleFungiHumansMicrobial Sensitivity TestsVoriconazoleAntifungal AgentsFluconazoleVoriconazoleantifungal susceptibility testing

Identifiers

PMID35852368
PMCPMC9380569
OpenAlexW4285796709

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.