ReviewAnnals of the New York Academy of Sciences2022
The promise of music therapy for Alzheimer's disease: A review.
Review in Annals of the New York Academy of Sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 6 syntheses or guidelines pooled it, 111 citations in OpenAlex.
- Global trends, research hotspots, and clinical evidence mapping of music therapy interventions for cognitive impairment: a bibliometric and visualization analysis from 2006 to 2026.Frontiers in psychology · 2026Pooled it
- Efficacy of music therapy as a non-pharmacological measure to support alzheimer's disease patients: a systematic review.BMC geriatrics · 2025Pooled it
- Use of Virtual Reality to Improve Spatial Orientation in Alzheimer's Disease and Mild Cognitive Impairment: A Systematic Review.Current Alzheimer research · 2024Pooled it
- Inconsistent Music-Based Intervention Reporting in Dementia Studies: A Systematic Mapping Review.Journal of Alzheimer's disease : JAD · 2024Pooled it
- Topical Cellular/Tissue and Molecular Aspects Regarding Nonpharmacological Interventions in Alzheimer's Disease-A Systematic Review.International journal of molecular sciences · 2023Pooled it
- Sensogenomics of music and Alzheimer's disease: An interdisciplinary view from neuroscience, transcriptomics, and epigenomics.Frontiers in aging neuroscience · 2023Pooled it
- A qualitative exploration of 40 Hz sound and music for older adults with mild cognitive impairment.Geriatric nursing (New York, N.Y.)Trial
- Translational potential of medicinal plants for Alzheimer's disease: integrated evidence from molecular mechanisms to preclinical and clinical findings.Natural products and bioprospecting · 2026Review
- Can Phonotherapy Serve as an Adjunct Treatment for Acute and Chronic Stroke? A Preliminary Report.Healthcare (Basel, Switzerland) · 2026Article
- MusicAlzheimer: AI-Powered, Culturally Tailored Digital Music Therapy Prototype for Alzheimer Disease Care.JMIR formative research · 2026Article
- A narrative review on the psychological mechanisms and efficacy of music interventions for improving symptoms of patients with ADHD.Frontiers in psychology · 2026Review
- Monoclonal antibodies and small molecules: on the cutting edge of Alzheimer's disease therapy.Frontiers in cell and developmental biology · 2026Review
- Psychophysiological effects of low-frequency sound mediated by room size, room shape, and stimulus duration.Frontiers in cognition · 2026Article
- Music activities that most elicit interest and pleasure among older people with mild-to-moderate dementia: a qualitative multiple-case study in Italy.Frontiers in aging neuroscience · 2026Article
- Review
- Wearable monitoring during music-based interventions in dementia: physiological and behavioral observations from a pilot study.Frontiers in human neuroscience · 2026Article
- Alzheimer Syndrome or Age-Related Dementia-History, Therapy and Prevention.Journal of clinical medicine · 2025Article
- Sex dependency of subconscious visual perception.Biology of sex differences · 2025Article
- Patients' experiences and needs of undergoing holmium laser enucleation of the prostate in the surgical process: a qualitative study.BMC urology · 2025Article
- Embodied Approach to Autobiographical Recall Disorders in Alzheimer's Disease.Neuropsychology review · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alzheimer's disease (AD) is a progressive neurodegenerative disease associated with cognitive decline. Memory problems are typically among the first signs of cognitive impairment in AD, and they worsen considerably as the disease progresses. However, musical memory is partially spared in patients with AD, despite severe deficits in episodic (and partly semantic) memory. AD patients can learn new songs, encode novel verbal information, and react emotionally to music. These effects of music have encouraged the use and development of music therapy (MT) for AD management. MT is easy to implement and well-tolerated by most patients and their caregivers. Effects of MT in patients with AD include improved mood, reduced depressive scores and trait anxiety, enhanced autobiographical recall, verbal fluency, and cognition. Here, we review musical memory in AD, therapeutic effects of studies using MT on AD, and potential mechanisms underlying those therapeutic effects. We argue that, because AD begins decades before the presentation of clinical symptoms, music interventions might be a promising means to delay and decelerate the neurodegeneration in individuals at risk for AD, such as individuals with genetic risk or subjective cognitive decline.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.