Evidence map›Paper›PMID 35851931›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2022

Clinical and microbiological characteristics of reflux cholangitis following bilio-enteric anastomosis.

Audrey Le Bot, Aurélien Sokal, Anaïs Choquet, Frédérique Maire, Bruno Fantin, Alain Sauvanet, Victoire de Lastours

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07509346 (Multicenter Clinical Trial to Evaluate the Efficacy and Safety of Fecal Microbiota Transplantation Versus Standard Treatment in Patients With Recurrent Non-Obstructive Acute Cholangitis - COLANBIOTA Trial), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07509346 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Multicenter Clinical Trial to Evaluate the Efficacy and Safety of Fecal Microbiota Transplantation Versus Standard Treatment in Patients With Recurrent Non-Obstructive Acute Cholangitis - COLANBIOTA Trial

TypeinterventionalSponsorPuerta de Hierro University HospitalRan2026 to 2029Enrolled44ConditionsCholangitis Acute, RecurrenceArmsFecal Microbial Transplantation
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Audrey Le BotInfectious Diseases and Intensive Care Unit, Pontchaillou University Hospital, Université Rennes 1, Rennes, France.
Aurélien SokalService de Médecine Interne, Hôpital Beaujon, Assistance-Publique des Hôpitaux de Paris, Université Paris Cité, 100 boulevard du Général Leclerc, 92110, Clichy, France.
Anaïs ChoquetService de Chirurgie Hépatobiliaire, Hôpital Beaujon, Assistance-Publique des Hôpitaux de Paris, Université Paris Cité, Clichy, France.
Frédérique MaireService de Gastro-Entérologie Et Pancréatologie, Hôpital Beaujon, Assistance-Publique des Hôpitaux de Paris, Université Paris Cité, Clichy, France.
Bruno FantinService de Médecine Interne, Hôpital Beaujon, Assistance-Publique des Hôpitaux de Paris, Université Paris Cité, 100 boulevard du Général Leclerc, 92110, Clichy, France.
Alain SauvanetService de Chirurgie Hépatobiliaire, Hôpital Beaujon, Assistance-Publique des Hôpitaux de Paris, Université Paris Cité, Clichy, France.
Victoire de LastoursService de Médecine Interne, Hôpital Beaujon, Assistance-Publique des Hôpitaux de Paris, Université Paris Cité, 100 boulevard du Général Leclerc, 92110, Clichy, France. victoire.de-lastours@aphp.fr.
Université Paris Cité · FRAssistance Publique – Hôpitaux de Paris · FRCentre Hospitalier Universitaire de Rennes · FRInfection, Anti-microbiens, Modélisation, Evolution

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Twenty-five patients with reflux cholangitis (RC) defined as acute cholangitis (AC) with normal abdominal imaging occurring > 3 months after bilioenteric anastomosis were described and compared to 116 AC patients with biliary obstruction (tumoral, lithiasis). RC episodes occurred a median 4.5 months after surgery; 18 (72%) had recurrent RC (n ≥ 3). RC episodes were less severe than obstructive AC; the outcome was favorable with short antibiotic courses and no selection of antibiotic-resistance. However, multiple recurrent RC occurred in 20 patients (80%). Prophylactic or pre-emptive antibiotics were successful in 3 and 11 patients. Revision surgery for jejunal loop lengthening was successful in 2/4 patients.

Indexed as

CholangitisAnastomosis, SurgicalAnti-Bacterial AgentsHumansReoperationAnti-Bacterial AgentsAcute cholangitisBiliary refluxBilioenteric anastomosis

Identifiers

PMID35851931
OpenAlexW4285800629

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.