Evidence map›Paper›PMID 35851651›Full record

ArticleDermatology and therapy2022

Healthcare Resource Utilization and Direct Cost of Patients with Atopic Dermatitis in Dubai, United Arab Emirates: A Retrospective Cohort Study.

Anwar Al Hammadi, Jaheersha Pakran, Mohamed Farghaly, Haytham Mohamed Ahmed, Amy Cha, Dilara Balkan, Sherif Afifi, Badarinath Chickballapur Ramachandrachar, Ashok Natarajan, Sreenivasulu Linga and 1 more

Open access · goldAbstract read
In one paragraph

Article in Dermatology and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Anwar Al HammadiDermamed Clinic, Dubai, UAE. alhammadi@dermamed.ae.
Jaheersha PakranM.D. Dermatology, Rashid Hospital, Dubai Health Authority, Dubai, UAE.
Mohamed FarghalyHealth Economics & Insurance Policies Department, Dubai Health Authority, Dubai, UAE.
Haytham Mohamed AhmedPfizer Inc. Ltd, Dubai, UAE.ORCID http://orcid.org/0000-0002-2883-3317
Amy ChaPfizer Inc. Ltd, New York, USA.
Dilara BalkanPfizer Inc. Ltd, Dubai, UAE.
Sherif AfifiPfizer Inc. Ltd, Dubai, UAE.
Badarinath Chickballapur RamachandracharIQVIA, Dubai, UAE.
Ashok NatarajanIQVIA, Dubai, UAE.
Sreenivasulu LingaIQVIA, Dubai, UAE.
Khadija Al JefriDermamed Clinic, Dubai, UAE.
Pfizer (United States) · USIQVIA (United Kingdom) · GBDubai Health Authority · AEUniversity Dermatology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAtopic dermatitis (AD) data are scarce in Dubai [United Arab Emirates (UAE)]. Therefore, this study aimed at understanding real-world healthcare resource utilization (HCRU) and related costs, specialties, treatment landscape, consultation-based prevalence and incidence, and patient characteristics.

methodsThis retrospective, longitudinal, insurance e-claims (Dubai Private Insurance-insured expatriates) database studied AD in Dubai between 1 January 2014 and 31 March 2020. Two cohorts of patients based on treatment status as the eligibility criteria were selected from 442,956 patients with at least two AD diagnosis claims: treated AD [mild to moderate (10,134 patients) and moderate to severe (3515 patients)] and untreated or on drugs not included in the treated AD cohort (10,806 patients).

resultsAcross treated AD (mild to moderate and moderate to severe) and untreated AD cohorts, mean age was ~ 29 years; the majority were from dermatology (65-44%) and pediatrics (29-32%) specialty. Key HCRU cost contributors were hospitalizations and outpatient visits in both the treated AD groups. Mean annual disease-specific HCRU cost per patient was highest for the moderate-to-severe treated (531.5 USD) cohort, followed by the mild-to-moderate treated (378.4 USD) cohort, and lowest for the untreated (144.0 USD) cohort; patients with AD with any infection, asthma, or allergic rhinitis showed a similar trend. However, AD-diagnosed patients with Staphylococcus infection had the highest mean HCRU cost among the mild-to-moderate treated AD cohort, followed by the moderate-to-severe treated AD cohort.

conclusionThis study indicated AD to be a common skin disease with a prevalence rate of 4-5% in Dubai (UAE), with the majority of patients (about 90%) being treated by specialists. However, there is a significant underuse of newer innovative therapies (including biologics). Also, disease severity (moderate-to-severe AD) was associated with high direct medical cost, which could be controlled by early intervention. Furthermore, AD treatment choice could focus on major direct HCRU cost contributors such as hospitalizations, comorbid conditions, and infections.

Indexed as

Atopic dermatitisClaims databaseDirect medical costDubaiHealthcare resource utilizationHealth policyReal-world study

Identifiers

PMID35851651
PMCPMC9294752
OpenAlexW4285798112

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.