ArticleNature plants2022
Genomic insights into historical improvement of heterotic groups during modern hybrid maize breeding.
Article in Nature plants, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
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69 citing papers in PubMed, 95 citations in OpenAlex.
- Temporal phenotypic responses of early vegetative maize to heat, drought, and combined stresses.The Plant journal : for cell and molecular biology · 2026Article
- Genome-Wide Association Mapping of Ear Traits in Early-Maturing Maize Under Contrasting Planting Densities.International journal of molecular sciences · 2026Article
- The OsUVR8-OsNAC3-OsERF117 signaling module mediates metabolic acclimation and climate adaptation in rice.Science advances · 2026Article
- Multiomics analysis of primary metabolism reveals the genetic basis of nitrogen partitioning modulated by ZmAVT1A-1 in maize.Nature genetics · 2026Article
- Achieving High-Density and Stress-Resilient Maize Breeding Via Germplasm Innovation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Identification of key candidate genes for body weight traits in male Dongfeng sika deer based on genome-wide association analysis.Scientific reports · 2026Article
- Genome-Wide Characterization of Long Non-Coding RNAs Identifies Candidate Regulatory Networks During Modern Maize Breeding.Plants (Basel, Switzerland) · 2026Article
- Dynamics of Gene and Allelic Expression During Modern Hybrid Maize Breeding.Plant biotechnology journal · 2026Article
- Genome-wide association study dissects the genetic architecture of kernel rate and its component traits in maize.BMC plant biology · 2026Article
- The incomplete dominance of gene expression controlled by Trans-eQTL hotspots contributes to heterosis in maize.Nature communications · 2026Article
- Chromatin accessibility landscape and its association with heterosis in maize hybrids.Nature communications · 2026Article
- Adoption of Standard Reference SNP Identifiers in Agricultural Genomics for Interoperability and Data Reuse.Scientific data · 2026Article
- Divergent genetic and phenotypic trajectories in China' s maize hybrids.BMC genomics · 2026Article
- Breeding ideotype maize with enhanced yield through genomics-guided pyramiding of favorable alleles.Nature genetics · 2026Article
- Article
- ClAPRT3-Mediated Adenine Salvage Pathway Enhances Purine Metabolites to Sustain Seed Vigour During Selfing in Cunninghamia lanceolata.Plant biotechnology journal · 2026Article
- Unlocking tropical adaptation: novel flowering time genes implicate JA and ROS signaling in maize.BMC plant biology · 2026Article
- Gene action, combining ability, heterotic grouping and hybrid performance of tropical maize inbred lines from a public breeding program in Brazil.Frontiers in plant science · 2026Article
- Genetic characterization of commercial spring maize germplasm in Northern China for hybrid breeding and trait improvement.Frontiers in plant science · 2026Article
- Integrated genomic analysis of a diverse maize population reveals novel genes and superior predictive models for ear diameter.BMC genomics · 2025Article
9 more citing papers are in PubMed but not listed here.
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Authors and funding
26 authors at 9 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Single-cross maize hybrids display superior heterosis and are produced from crossing two parental inbred lines belonging to genetically different heterotic groups. Here we assembled 1,604 historically utilized maize inbred lines belonging to various female heterotic groups (FHGs) and male heterotic groups (MHGs), and conducted phenotyping and genomic sequencing analyses. We found that the FHGs and MHGs have undergone both convergent and divergent changes for different sets of agronomic traits. Using genome-wide selection scans and association analyses, we identified a large number of candidate genes that contributed to the improvement of agronomic traits of the FHGs and MHGs. Moreover, we observed increased genetic differentiation between the FHGs and MHGs across the breeding eras, and we found a positive correlation between increasing heterozygosity levels in the differentiated genes and heterosis in hybrids. Furthermore, we validated the function of two selected genes and a differentiated gene. This study provides insights into the genomic basis of modern hybrid maize breeding.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.