ReviewTrends in cell biology2022
Nutrient availability as an arbiter of cell size.
Review in Trends in cell biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- Article
- Integrative role of CTPS cytoophidia in polyploid tissue growth and nutrient adaptation.Insect science · 2026Article
- mSphere of Influence: The bacterial growth law-revisiting the old to discover the new.mSphere · 2026Article
- A coma pattern-based autofocusing method resolves bacterial cold shock response at single-cell level.eLife · 2026Article
- Ovoid cell is an inducible small-sized morphotype that enhances proliferation and antifungal drug tolerance in the human fungal pathogen Cryptococcus neoformans.PLoS pathogens · 2026Article
- Cells Dynamically Adapt Their Nuclear Volumes and Proliferation Rates During Single to Multicellular Transitions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Deep-learning deconvolution and segmentation of fluorescent membranes for high-precision bacterial cell-size profiling.Communications biology · 2026Article
- Uncoupling of nutrient sensing and cell size control by specific defects in ceramide structure.Biology open · 2026Article
- The role of cell growth rate on accumulation of the mitotic cyclin Cdc13 in fission yeast.bioRxiv : the preprint server for biology · 2026Article
- Fission yeast cells use distinct cell size control mechanisms to regulate cell geometry in response to osmotic, oxidative, or low glucose conditions.Molecular biology of the cell · 2026Article
- A MAP kinase cascade modulates expression of late G1 phase cyclins in budding yeast.bioRxiv : the preprint server for biology · 2025Article
- Tumour Cell Size Control and Its Impact on Tumour Cell Function.Cell proliferation · 2025Review
- Sea Ice Loss leads to regime shifts in the arctic biological pump.Nature communications · 2025Article
- Diverse biophysical and molecular mechanisms drive phytoplankton sinking in response to starvation.PLoS biology · 2025Article
- A growing problem: The many unsolved mysteries of cell growth.Molecular biology of the cell · 2025Review
- Investigating the Effects of Hydraulic Shear onMicroorganisms · 2025Article
- Biophysical and molecular mechanisms responsible for phytoplankton sinking in response to starvation.bioRxiv : the preprint server for biology · 2025Article
- Determination of Nutrients, Biomass, and Bacterial Quantification in Different Mangroves Sites: A Comparative Study on Nutrients Dependent Biomass Production.Ecology and evolution · 2025Article
- Eukaryotic cell size regulation and its implications for cellular function and dysfunction.Physiological reviews · 2024Review
- Cell growth and nutrient availability control the mitotic exit signaling network in budding yeast.The Journal of cell biology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Pioneering work carried out over 60 years ago discovered that bacterial cell size is proportional to the growth rate set by nutrient availability. This relationship is traditionally referred to as the 'growth law'. Subsequent studies revealed the growth law to hold across all orders of life, a remarkable degree of conservation. However, recent work suggests the relationship between growth rate, nutrients, and cell size is far more complicated and less deterministic than originally thought. Focusing on bacteria and yeast, here we review efforts to understand the molecular mechanisms underlying the relationship between growth rate and cell size.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.