Evidence map›Paper›PMID 35851273›Full record

ArticleScientific data2022

Transcriptomic study of anastasis for reversal of ethanol-induced apoptosis in mouse primary liver cells.

Ho Man Tang, C Conover Talbot, Ming Chiu Fung, Ho Lam Tang

Open access · goldAbstract readDataset
In one paragraph

Article in Scientific data, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ho Man TangSchool of Life Sciences, Chinese University of Hong Kong, Shatin, Hong Kong SAR, China. tang@link.cuhk.edu.hk.ORCID 0000-0002-7730-3013
C Conover TalbotInstitute for Basic Biomedical Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.ORCID 0000-0002-3758-2425
Ming Chiu FungSchool of Life Sciences, Chinese University of Hong Kong, Shatin, Hong Kong SAR, China. mingchiufung@cuhk.edu.hk.
Ho Lam TangDepartment of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. holamtang@jhmi.edu.ORCID 0000-0002-6889-6937
Johns Hopkins University · USChinese University of Hong Kong · HK

Funding

Cell survival by anastasis, a novel therapeutic target in cancerK22CA204458 · NCI · JOHNS HOPKINS UNIVERSITY · PI TANG, HO LAM · 2017 to 2019
$486k
Anastasis biosensor for tracking reversal of apoptosis in vivoR21OD028764 · OD · JOHNS HOPKINS UNIVERSITY · PI TANG, HO LAM · 2020 to 2021
$442k
Elucidating connections between anastasis and cancer drug resistanceR21CA249362 · NCI · JOHNS HOPKINS UNIVERSITY · PI TANG, HO LAM · 2020 to 2020
$411k
NCI NIH HHS K22 CA204458NCI NIH HHS R21 CA249362NIH HHS R21 OD028764
6 · The paper itself

Abstract

Anastasis is a cell recovery mechanism that rescues dying cells from the brink of death. Reversal of apoptosis is the first example of anastasis. Here, we describe a comprehensive dataset containing time-course mRNA expression profiles for reversal of ethanol-induced apoptosis in mouse primary liver cells in νitro. This transcriptome dataset includes the conditions of the untreated cells, cells undergoing apoptosis triggered by incubating with cell death inducer of 4.5% ethanol for 5 hours, and apoptosis reversal of ethanol-induced cells at the early (3

Indexed as

ApoptosisEthanolLiverTranscriptomeAnimalsCell Death ReversalMiceEthanol

Identifiers

PMID35851273
PMCPMC9293995
OpenAlexW4285731452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.