Evidence map›Paper›PMID 35851050›Full record

ArticleScientific reports2022

Microdosimetry performance of the first multi-arrays of 3D-cylindrical microdetectors.

Diana Bachiller-Perea, Mingming Zhang, Celeste Fleta, David Quirion, Daniela Bassignana, Faustino Gómez, Consuelo Guardiola

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Diana Bachiller-PereaUniversité Paris-Saclay, CNRS/IN2P3, IJCLab, 91405, Orsay, France. bachiller@ijclab.in2p3.fr.
Mingming ZhangUniversité Paris-Saclay, CNRS/IN2P3, IJCLab, 91405, Orsay, France.
Celeste FletaInstituto de Microelectrónica de Barcelona (IMB-CNM, CSIC), 08193, Barcelona, Spain.
David QuirionInstituto de Microelectrónica de Barcelona (IMB-CNM, CSIC), 08193, Barcelona, Spain.
Daniela BassignanaInstituto de Microelectrónica de Barcelona (IMB-CNM, CSIC), 08193, Barcelona, Spain.
Faustino GómezDepartamento de Física de Partículas, Universidad de Santiago de Compostela, 15782, Santiago de Compostela, Spain.
Consuelo GuardiolaUniversité Paris-Saclay, CNRS/IN2P3, IJCLab, 91405, Orsay, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present work reports on the microdosimetry measurements performed with the two first multi-arrays of microdosimeters with the highest radiation sensitive surface covered so far. The sensors are based on new silicon-based radiation detectors with a novel 3D cylindrical architecture. Each system consists of arrays of independent microdetectors covering 2 mm[Formula: see text]2 mm and 0.4 mm[Formula: see text]12 cm radiation sensitive areas, the sensor distributions are arranged in layouts of 11[Formula: see text]11 microdetectors and 3[Formula: see text]3 multi-arrays, respectively. We have performed proton irradiations at several energies to compare the microdosimetry performance of the two systems, which have different spatial resolution and detection surface. The unitcell of both arrays is a 3D cylindrical diode with a 25 [Formula: see text]m diameter and a 20 [Formula: see text]m depth that results in a welldefined and isolated radiation sensitive micro-volume etched inside a silicon wafer. Measurements were carried out at the Accélérateur Linéaire et Tandem à Orsay (ALTO) facility by irradiating the two detection systems with monoenergetic proton beams from 6 to 20 MeV at clinical-equivalent fluence rates. The microdosimetry quantities were obtained with a spatial resolution of 200 [Formula: see text]m and 600 [Formula: see text]m for the 11[Formula: see text]11 system and for the 3[Formula: see text]3 multi-array system, respectively. Experimental results were compared with Monte Carlo simulations and an overall good agreement was found. The good performance of both microdetector arrays demonstrates that this architecture and both configurations can be used clinically as microdosimeters for measuring the lineal energy distributions and, thus, for RBE optimization of hadron therapy treatments. Likewise, the results have shown that the devices can be also employed as a multipurpose device for beam monitoring in particle accelerators.

Indexed as

Proton TherapyRadiometryMonte Carlo MethodProtonsSiliconProtonsSilicon

Identifiers

PMID35851050
PMCPMC9293924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.