Evidence map›Paper›PMID 35850990›Full record

ArticleInternal medicine (Tokyo, Japan)2022

Successful Elimination of SARS-CoV-2 Following Vaccination with BNT162b2 after Prolonged Viral Infection in an Immunocompromised Lymphoma Patient.

Masao Hagihara, Yui Imai, Tomoyuki Uchida, Shin Ohara, Morihiro Inoue, Tomiyuki Sugi, Keiko Mitamura

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Prolonged viral pneumonia and high mortality in COVID-19 patients on anti-CD20 monoclonal antibody therapy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Masao HagiharaDepartment of Hematology, Eiju General Hospital, Japan.
Yui ImaiDepartment of Hematology, Eiju General Hospital, Japan.
Tomoyuki UchidaDepartment of Hematology, Eiju General Hospital, Japan.
Shin OharaDepartment of Hematology, Eiju General Hospital, Japan.
Morihiro InoueDepartment of Hematology, Eiju General Hospital, Japan.
Tomiyuki SugiDepartment of Pharmacy, Eiju General Hospital, Japan.
Keiko MitamuraDepartment of Preventive Medicine, Eiju General Hospital, Japan.
Eiju General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 52-year-old man with mantle cell lymphoma treated with bendamustine and rituximab developed prolonged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Despite elevated titers of anti-spike IgG antibody, protracted pancytopenia persisted for more than six months. Finally, the anti-SARS CoV-2 vaccine, BNT162b2, was administered, which improved his blood cell count and eliminated the virus. The increased anti-spike IgG titer and lymphocyte count after vaccination suggested that both humoral and cellular immunity acted in coordination to eliminate the virus.

Indexed as

COVID-19LymphomaViral VaccinesAdultAntibodies, ViralBNT162 VaccineHumansMaleMiddle AgedSARS-CoV-2VaccinationAntibodies, ViralBNT162 VaccineViral Vaccinesanti-spike IgGbendamustinecellular immunityprolonged infectionSARS-CoV-2vaccine

Identifiers

PMID35850990
PMCPMC9381351
OpenAlexW4285491188

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.