Evidence map›Paper›PMID 35850489›Full record

ArticleJournal of the American Chemical Society2022

Further Dimensions for Sensing in Biofluids: Distinguishing Bioorganic Analytes by the Salt-Induced Adaptation of a Cucurbit[7]uril-Based Chemosensor.

Changming Hu, Thomas Jochmann, Papri Chakraborty, Marco Neumaier, Pavel A Levkin, Manfred M Kappes, Frank Biedermann

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. An Engineered Supramolecular Pathway for Enhanced Electrochemiluminescence.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
  3. Review
  4. HalogenatedRSC advances · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Changming HuInstitute of Nanotechnology (INT), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz-1, Eggenstein-Leopoldshafen 76344, Germany.ORCID 0000-0002-1220-003X
Thomas JochmannDepartment of Computer Science and Automation, Technische Universität Ilmenau, Gustav-Kirchhoff-Str. 2, Ilmenau 98693, Germany.ORCID 0000-0002-3564-4127
Papri ChakrabortyInstitute of Nanotechnology (INT), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz-1, Eggenstein-Leopoldshafen 76344, Germany.ORCID 0000-0002-1353-7734
Marco NeumaierInstitute of Nanotechnology (INT), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz-1, Eggenstein-Leopoldshafen 76344, Germany.ORCID 0000-0002-3810-3377
Pavel A LevkinInstitute of Biological and Chemical Systems - Functional Molecular Systems (IBCS-FMS), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz Platz-1, Eggenstein-Leopoldshafen 76344, Germany.
Manfred M KappesInstitute of Nanotechnology (INT), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz-1, Eggenstein-Leopoldshafen 76344, Germany.ORCID 0000-0002-1199-1730
Frank BiedermannInstitute of Nanotechnology (INT), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz-1, Eggenstein-Leopoldshafen 76344, Germany.ORCID 0000-0002-1077-6529

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insufficient binding selectivity of chemosensors often renders biorelevant metabolites indistinguishable by the widely used indicator displacement assay. Array-based chemosensing methods are a common workaround but require additional effort for synthesizing a chemosensor library and setting up a sensing array. Moreover, it can be very challenging to tune the inherent binding preference of macrocyclic systems such as cucurbit[

Indexed as

Bridged-Ring CompoundsImidazolesCucurbit(n)urilsHeterocyclic Compounds, 2-RingHumansImidazolidinesMacrocyclic CompoundsBridged-Ring Compoundscucurbit(7)urilCucurbit(n)urilsHeterocyclic Compounds, 2-RingImidazolesImidazolidinesMacrocyclic Compounds

Identifiers

PMID35850489
PMCPMC9335531

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.