ArticleBrain and behavior2022
Quantitative changes in mental health measures with 3MDR treatment for Canadian military members and veterans.
Article in Brain and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 12 citations in OpenAlex.
- 3MDR Therapy Reduces Symptoms of PTSD and Related Conditions in Canadian Military Members and Veterans, Public Safety Personnel, and Clinical Personnel.Brain and behavior · 2026Trial
- Moving Forward from Moral Injury: A Mixed Methods Study Investigating the Use of 3MDR for Treatment-Resistant PTSD.International journal of environmental research and public health · 2023Trial
- Toward a definition of treatment-resistant posttraumatic stress disorder: A systematic review.Journal of military, veteran and family health · 2026Review
- 3MDR: From rehabilitation technology to a transformative trauma therapy for posttraumatic stress disorder.Journal of military, veteran and family health · 2026Article
- Multi-Modal Motion-Assisted Memory Desensitization and Reconsolidation (3MDR) Treatment for Postpartum Posttraumatic Stress Disorder (PTSD) from Grief: A Case Report.Psychiatry and clinical psychopharmacology · 2025Article
- Brief Manual for Multi-Modal Motion-Assisted Memory Desensitization and Reconsolidation Therapy for the Treatment of Post-traumatic Stress Disorder.Psychiatry and clinical psychopharmacology · 2025Article
- Case Report: Multi-modal motion-assisted memory desensitization and reconsolidation for traumatic grief (3MDR-TG).Frontiers in psychology · 2025Article
- Treatment of Posttraumatic Stress Disorder: A State-of-the-art Review.Current neuropharmacology · 2024Review
- Virtual realities, real recoveries: exploring the efficacy of 3MDR therapy for treatment-resistant PTSD.Frontiers in psychology · 2024Review
- Article
- Quantitative changes in mental health measures with 3MDR treatment for Canadian military members and veterans.Brain and behavior · 2022Article
- Decreased Emotional Dysregulation Following Multi-Modal Motion-Assisted Memory Desensitization and Reconsolidation Therapy (3MDR): Identifying Possible Driving Factors in Remediation of Treatment-Resistant PTSD.International journal of environmental research and public health · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveMilitary members and veterans are at elevated risk of treatment-resistant posttraumatic stress disorder (TR-PTSD) due to higher rates of exposure to potentially traumatic events during the course of duty. Knowledge of TR-PTSD is limited, and specific protocols or evidence-based TR-PTSD therapies are lacking. Multimodal motion-assisted memory desensitization and reconsolidation (3MDR) therapy is an emerging intervention for combat-related TR-PTSD. The purpose of this study was to preliminarily assess the effectiveness of 3MDR in addressing TR-PTSD in Canadian military members and veterans.
methodsThis study is a longitudinal mixed-methods clinical trial. English-speaking military members and veterans aged 18-60 with TR-PTSD were recruited to participate. The intervention consisted of six sessions of 3MDR therapy. Quantitative data were collected pretreatment, posttreatment, and longitudinally at 1, 3, and 6 months after completion of 3MDR.
resultsResults from the first 11 participants to complete the 3MDR protocol exhibited statistically significant improvement (surviving multiple comparison correction) in clinically administered and self-reported scores for PTSD (CAPS-5 and PCL-5), moral injury (MISS-M-SF), depression (PHQ-9), anxiety (GAD-7), emotional regulation (DERS-18), and resilience (CD-RS-25).
conclusionThe preliminary and exploratory results from this clinical trial support the growing body of literature illustrating 3MDR as an effective treatment for military-related TR-PTSD. These results are notable given participants' previous lack of success with frontline psychotherapeutic and pharmacological interventions. Given that there are currently very limited treatment options for TR-PTSD, 3MDR could prove to be a valuable treatment option for military members and veterans with TR-PTSD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.