Evidence map›Paper›PMID 35849311›Full record

ArticleNeuroscience bulletin2022

Reading-related Brain Function Restored to Normal After Articulation Training in Patients with Cleft Lip and Palate: An fMRI Study.

Liwei Sun, Wenjing Zhang, Mengyue Wang, Songjian Wang, Zhen Li, Cui Zhao, Meng Lin, Qian Si, Xia Li, Ying Liang and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroscience bulletin, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. White matter tract integrity in isolated oral clefts: relationship to cognition and reading skills.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Liwei Sun *School of Biomedical Engineering, Capital Medical University, Beijing, 100069, China.
Wenjing Zhang *Beijing Stomatological Hospital, Capital Medical University, Beijing, 100050, China.
Mengyue Wang *School of Life Science, Beijing Institute of Technology, Beijing, 100081, China.
Songjian WangBeijing Institute of Otolaryngology-Head and Neck Surgery, Beijing, 100005, China.
Zhen LiDepartment of Ultrasound, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100026, China.
Cui ZhaoSchool of Biomedical Engineering, Capital Medical University, Beijing, 100069, China.
Meng LinPeking University First Hospital, Beijing, 100034, China.
Qian SiSchool of Biomedical Engineering, Capital Medical University, Beijing, 100069, China.
Xia LiSchool of Biomedical Engineering, Capital Medical University, Beijing, 100069, China.
Ying LiangSchool of Biomedical Engineering, Capital Medical University, Beijing, 100069, China.
Jing WeiSchool of Biomedical Engineering, Capital Medical University, Beijing, 100069, China.
Xu ZhangSchool of Biomedical Engineering, Capital Medical University, Beijing, 100069, China. zhangxu@ccmu.edu.cn.
Renji ChenBeijing Stomatological Hospital, Capital Medical University, Beijing, 100050, China. chenrenji@126.com.
Chunlin LiSchool of Biomedical Engineering, Capital Medical University, Beijing, 100069, China. lichunlin1981@163.com.
Capital Medical University · CNBeijing Institute of Neurosurgery · CNBeijing Institute of Technology · CNBeijing Obstetrics and Gynecology Hospital · CNPeking University First Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cleft lip and/or palate (CLP) are the most common craniofacial malformations in humans. Speech problems often persist even after cleft repair, such that follow-up articulation training is usually required. However, the neural mechanism behind effective articulation training remains largely unknown. We used fMRI to investigate the differences in brain activation, functional connectivity, and effective connectivity across CLP patients with and without articulation training and matched normal participants. We found that training promoted task-related brain activation among the articulation-related brain networks, as well as the global attributes and nodal efficiency in the functional-connectivity-based graph of the network. Our results reveal the neural correlates of effective articulation training in CLP patients, and this could contribute to the future improvement of the post-repair articulation training program.

Indexed as

Cleft LipCleft PalateBrainHumansMagnetic Resonance ImagingReadingArticulation trainingfMRIFunctional connectivityGraph-based network analysisNon-syndromic cleft lip and palate

Identifiers

PMID35849311
PMCPMC9554179
OpenAlexW4285730264

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.