Evidence map›Paper›PMID 35849224›Full record

ArticleCell and tissue banking2023

Biochemical aspects of effects of mesenchymal stem cell treatment in chronic wounds progressive healing.

Anjali Athanerey, Neha Rani Verma, Piyush Bhargava, Dnyanesh Amle, P K Patra, Awanish Kumar

Abstract read
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Article in Cell and tissue banking, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anjali AthanereyDepartment of Biotechnology, National Institute of Technology Raipur, Raipur, Chhattisgarh, India.
Neha Rani VermaDepartment of Biochemistry, Pt JNM Medical College Raipur, Raipur, Chhattisgarh, India.
Piyush BhargavaDepartment of Biochemistry, Pt JNM Medical College Raipur, Raipur, Chhattisgarh, India.
Dnyanesh AmleDepartment of Biochemistry, AIIMS Nagpur, Sumthana, Maharastra, India.
P K PatraDepartment of Biochemistry, Pt JNM Medical College Raipur, Raipur, Chhattisgarh, India. pkp1964@yahoo.co.in.
Awanish KumarDepartment of Biotechnology, National Institute of Technology Raipur, Raipur, Chhattisgarh, India. drawanishkr@gmail.com.ORCID http://orcid.org/0000-0001-8735-479X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic wounds are a persistent burden for medical professionals. Despite developments and advancements in treatment, these wounds do not heal completely. Mesenchymal stem cells (MSCs) are the epicenter of regenerative medicine that have shown promising results in chronic wound regeneration. Autologous peripheral blood-derived MSCs (PB-MSCs) are comparatively new in wound healing treatment, bone-marrow-derived MSCs (BM-MSCs), and adipose-derived stem cells (ADSCs) are commonly being practiced. In the present study, PB-MSCs treatment was given to chronic wound patients. Various biochemical parameters like random blood glucose, serum urea, serum creatinine, bilirubin (total and direct), Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT), total protein, albumin levels, and association of other factors/conditions such as age, sex, addiction of drug/alcohol were also evaluated/compared with complete and without complete healing. The wound area of the ulcer was found to be significantly reduced and the wound was healthier after the treatment. These biochemical parameters could be certainly utilized as biomarkers to anticipate the risk of chronic wounds. These findings may contribute to the development of better wound care treatment strategies and drug discovery in the field of regenerative medicine.

Indexed as

Mesenchymal Stem CellsMesenchymal Stem Cell TransplantationHumansWound HealingBiochemical markersChronic woundsMesenchymal stem cellsTreatment

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.