ArticleAmerican journal of respiratory and critical care medicine2022
Transcriptional Circuitry of NKX2-1 and SOX1 Defines an Unrecognized Lineage Subtype of Small-Cell Lung Cancer.
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Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
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Who cites it
20 citing papers in PubMed, 24 citations in OpenAlex.
- NKX2-1 regulates cell survival, maturation, and DNAdamage responses as a cofactor of RUNX1 in T-cell acute lymphoblastic leukemia.Haematologica · 2026Article
- Bidirectional coupling among EMT, AXL-RB1 signaling and lineage switch drives resistance to osimertinib and worse clinical outcomes in NSCLC.bioRxiv : the preprint server for biology · 2026Article
- Functional roles and clinical potential of SOX1 in cancer as a biomarker and therapeutic target.Discover oncology · 2026Review
- Improvement of prognosis among patients with lung adenocarcinoma through precision therapy: analysis based on The Cancer Genome Atlas.Translational cancer research · 2026Article
- Lack of caspase 8 directs neuronal progenitor-like reprogramming and small cell lung cancer progression.Nature communications · 2025Article
- Comprehensive Genomic Profiling of Small-Cell Lung Cancer Reveals Frequent Potentially Targetable Alterations.International journal of molecular sciences · 2025Article
- Persistent lineage plasticity driving lung cancer development and progression.Clinical and translational medicine · 2025Review
- Ginsenoside Rg1 alleviates chronic stress-induced depression in rats by targeting Cx43-YAP axis.Acta pharmacologica Sinica · 2025Article
- Epigenomic analysis identifies DTP subpopulation using HOPX to develop targeted therapy resistance in lung adenocarcinoma.iScience · 2025Article
- Molecular Subtypes and Targeted Therapeutic Strategies in Small Cell Lung Cancer: Advances, Challenges, and Future Perspectives.Molecules (Basel, Switzerland) · 2025Review
- Enhancer reprogramming: critical roles in cancer and promising therapeutic strategies.Cell death discovery · 2025Review
- Candidate Biomarker of Response to Immunotherapy In Small Cell Lung Cancer.Current treatment options in oncology · 2025Review
- WTAP Regulates SOX1 Expression to Affect the Tumorigenicity of Colorectal Cancer via an mDigestive diseases and sciences · 2025Article
- Intratumoral heterogeneity and potential treatment strategies in small cell lung cancer.Frontiers in oncology · 2025Review
- Super-enhancer-driven IRF2BP2 enhances ALK activity and promotes neuroblastoma cell proliferation.Neuro-oncology · 2024Article
- Small cell lung cancer profiling: an updated synthesis of subtypes, vulnerabilities, and plasticity.Trends in cancer · 2024Review
- Autophagic flux modulates tumor heterogeneity and lineage plasticity in SCLC.Frontiers in oncology · 2024Article
- Pathogenic role of super-enhancers as potential therapeutic targets in lung cancer.Frontiers in pharmacology · 2024Review
- New Insights into the Epigenomic Landscape of Small-Cell Lung Cancer: A Game Changer?American journal of respiratory and critical care medicine · 2022Article
- Transcriptional Circuitry of NKX2-1 and SOX1 Defines an Unrecognized Lineage Subtype of Small-Cell Lung Cancer.American journal of respiratory and critical care medicine · 2022Article
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Authors and funding
22 authors at 10 institutions in 4 countries.
Ranran KongDepartment of Thoracic Surgery and.ORCID 0000-0002-3658-8745
Ayushi S PatelDivision of Pulmonary, Critical Care and Sleep Medicine.
Takashi SatoDivision of Pulmonary, Critical Care and Sleep Medicine.
Feng JiangDivision of Pulmonary, Critical Care and Sleep Medicine.
Seungyeul YooDepartment of Genetics and Genomic Sciences, and.
Li BaoPeople's Hospital of Ningxia Hui Autonomous Region, Yinchuan, China.
Abhilasha SinhaDivision of Pulmonary, Critical Care and Sleep Medicine.
Yang TianDivision of Pulmonary, Critical Care and Sleep Medicine.
Maya FridrikhDivision of Pulmonary, Critical Care and Sleep Medicine.
Shuhui LiuDivision of Infectious Diseases, Department of Medicine.
Jie FengDepartment of Nephrology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Xijing HeDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Jiantao JiangDepartment of Thoracic Surgery and.
Yuefeng MaDepartment of Thoracic Surgery and.
Karina GrullonDivision of Pulmonary, Critical Care and Sleep Medicine.
Dawei YangDivision of Pulmonary, Critical Care and Sleep Medicine.
Charles A PowellDivision of Pulmonary, Critical Care and Sleep Medicine.
Mary Beth BeasleyDepartment of Pathology and Laboratory Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.ORCID 0000-0003-2340-1897
Jun ZhuTisch Cancer Institute.
Eric L SnyderDepartment of Pathology.
Shaomin LiDepartment of Thoracic Surgery and.
Hideo WatanabeDivision of Pulmonary, Critical Care and Sleep Medicine.ORCID 0000-0002-6017-6361
Cancer Institute (WIA) · INFirst Affiliated Hospital of Xi'an Jiaotong University · CNFudan University · CNIcahn School of Medicine at Mount Sinai · USKeio University · JPOffice of Infectious Diseases · USSema4 (United States) · USThe Fourth People's Hospital of Ningxia Hui Autonomous Region · CNUniversity of Utah · USXi'an International Studies University · CN
Funding
Transcriptional Regulation of Lung Cancer IdentityR01CA212415 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Eric Lee Snyder · 2017 to 2026
$3.2MPatho-Genetic Analysis of Invasive Mucinous Adenocarcinoma of the LungR01CA240317 · NCI · CINCINNATI CHILDRENS HOSP MED CTR · PI MAEDA, YUTAKA, SNYDER, ERIC LEE · 2020 to 2024
$3.1MLineage heterogeneity and plasticity in lung cancerR01CA240342 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WATANABE, HIDEO · 2019 to 2023
$2.9MLung Adenocarcinoma Invasion GenomicsR01CA163772 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MASSION, PIERRE P., POWELL, CHARLES A. · 2013 to 2017
$2.9MCOVID and Translational Science supercomputer (CATS)S10OD030463 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2021 to 2021
$2.0MNCI NIH HHS R01 CA163772NCI NIH HHS R01 CA212415NCI NIH HHS R01 CA240317NCI NIH HHS R01 CA240342NIH HHS R01CA163772NIH HHS S10 OD030463
Abstract
PubMed holds no abstract for this paper.
Indexed as
Lung NeoplasmsSmall Cell Lung CarcinomaSOXB1 Transcription FactorsThyroid Nuclear Factor 1AnimalsCell Transformation, NeoplasticHumansLungMiceTranscription FactorsNKX2-1 protein, humanSOX1 protein, humanSOXB1 Transcription FactorsThyroid Nuclear Factor 1Transcription FactorsNKX2-1/TTF-1SCLCsmall-cell lung cancerSOX1superenhancer
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.