Evidence map›Paper›PMID 35848903›Full record

ArticleJournal of vision2022

Detection and discrimination of achromatic contrast: A ganglion cell perspective.

Barry B Lee, William H Swanson

Open access · goldAbstract read
In one paragraph

Article in Journal of vision, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Barry B LeeGraduate Center for Vision Research, Department of Biological Sciences, SUNY College of Optometry, New York, NY, USA.
William H SwansonIndiana University School of Optometry, Bloomington IN, USA.
Indiana University Bloomington · USSUNY College of Optometry · US

Funding

3D RNFL Structure And High-Resolution Perimetry For Assessing Glaucomatous DamageR01EY024542 · NEI · TRUSTEES OF INDIANA UNIVERSITY · PI SWANSON, WILLIAM H. · 2014 to 2023
$3.2M
INFORMATION TRANSFER THROUGH RETINAL GANGLION CELLSR01EY013112 · NEI · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI LEE, BARRY · 2000 to 2010
$2.6M
NEI NIH HHS R01 EY013112NEI NIH HHS R01 EY024542
6 · The paper itself

Abstract

The magnocellular (MC) pathway in the primate has much higher achromatic contrast sensitivity than the parvocellular (PC) pathway, and is implicated in luminance contrast detection. But MC pathway responses tend to saturate at lower achromatic contrast than do PC pathway responses. It has been proposed that the PC pathway plays a major role in discriminating suprathreshold achromatic contrast, because the MC pathway is in saturation. This has been termed the pulsed-pedestal protocol. To test this hypothesis, responses of MC and PC pathway ganglion cells have been examined under suprathreshold conditions with stimulus configurations similar to those in psychophysical tests. For MC cells, response saturation was much less for flashed or moving edges than for sinusoidal modulation, and MC cell thresholds predicted for these stimuli were similar to psychophysical discrimination (and detection) data. Results suggest the protocol is not effective in segregating MC and PC function.

Indexed as

Contrast SensitivityVisual PathwaysAnimalsNeuronsPhotic StimulationPsychophysics

Identifiers

PMID35848903
PMCPMC9308016
OpenAlexW4285726714

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.