Evidence map›Paper›PMID 35848848›Full record

ArticleCell cycle (Georgetown, Tex.)2022

LncRNA MINCR attenuates osteoarthritis progression via sponging miR-146a-5p to promote BMPR2 expression.

Dongyun Li, Xiaoying Wang, Tengda Yi, Lin Zhang, Lirui Feng, Mingxing Zhang, Yongsheng He, Shunkui Gang

Open access · greenAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Dongyun LiDepartment of Preventive Treatment of Disease, the Third Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming, China.
Xiaoying WangDepartment of Preventive Treatment of Disease, the Third Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming, China.
Tengda YiDepartment of Preventive Treatment of Disease, the Third Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming, China.
Lin ZhangDepartment of Preventive Treatment of Disease, the Third Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming, China.
Lirui FengDepartment of Preventive Treatment of Disease, the Third Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming, China.
Mingxing ZhangDepartment of Preventive Treatment of Disease, the Third Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming, China.
Yongsheng HeResearch and development center, The Yunnan Labreal Biotechnology Co., Ltd, Kunming, China.
Shunkui GangDepartment of Preventive Treatment of Disease, the Third Affiliated Hospital of Yunnan University of Traditional Chinese Medicine, Kunming, China.ORCID 0000-0002-2653-1403
Yunnan University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purposes of this study are to explore the function and regulatory mechanism of a novel lncRNA MYC-Induced Long non-coding RNA (MINCR) in osteoarthritis (OA). The expression of lncRNA MINCR, miR-146a-5p, and bone morphogenetic protein receptor 2 (BMPR2), Sry-type high-mobility-group box 9 (SOX9), collagen type II alpha 1 (COL2A1), Aggrecan, metalloproteinase with thrombospondin motifs-4 (ADAMTS-4), Matrix metalloproteinase 3 (MMP3), MMP13, COL2A1, and Aggrecan were determined using quantitative real-time PCR (qRT-PCR), western blot, immunohistochemistry (IHC) and immunofluorescence (IF)

Indexed as

MicroRNAsOsteoarthritisRNA, Long NoncodingAggrecansAnimalsApoptosisBone Morphogenetic Protein Receptors, Type IIChondrocytesIn Situ Hybridization, FluorescenceInterleukin-1betaRatsAggrecansBmpr2 protein, ratBone Morphogenetic Protein Receptors, Type IIInterleukin-1betaMicroRNAsRNA, Long NoncodingBMPR2inflammationMINCRmiR-146a-5pOsteoarthritis

Identifiers

PMID35848848
PMCPMC9645256
OpenAlexW4285802110

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.