ReviewAnaesthesia2022
The COVID-19 pandemic and its consequences for chronic pain: a narrative review.
Review in Anaesthesia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
52 citing papers in PubMed, 82 citations in OpenAlex.
- Review
- Long-term examination of pain and health-related outcomes in people with fibromyalgia before, during, and after COVID-19.Pain reports · 2026Article
- Feasibility study of home-based rehabilitation training for language disorders in infants aged 0-1 year.Frontiers in pediatrics · 2026Article
- Emergency department opioid prescribing trends among provider types: an analysis of the NHAMCS, 2019-2021.Internal and emergency medicine · 2026Observational
- Article
- Trends of rehabilitation needs in 195 countries and regions from 1990 to 2021 and the impact of the COVID-19 pandemic on it: a systematic analysis of the Global Burden of Disease Study 2021.International journal of surgery (London, England) · 2026Article
- Article
- Estimating Impact of SARS-CoV-2 Infection on Health-Related Quality of Life Among Persons Aged 8 Years and Older, August 2020-July 2022.Journal of health economics and outcomes research · 2026Article
- Monitoring and modulating interconnected physiological systems in space using portable closed-loop technologies.Frontiers in network physiology · 2026Article
- Pain experiences and pain management among patients with different pain locations in a high-density Asian city.Pain management · 2025Article
- Article
- Mu-opioid receptor expression on B cells as a potential biomarker for chronic pain: a follow-up study with patients with fibromyalgia.Pain reports · 2025Article
- Multiday intravenous ketamine infusion therapy for the management of central sensitisation syndrome secondary to chronic chemotherapy-induced peripheral neuropathic pain.BMJ case reports · 2025Article
- Article
- The Association Between COVID-19-Related Persistent Symptoms, Psychological Flexibility, and General Mental Health Among People With and Without Persistent Pain in the UK.Clinics and practice · 2025Article
- Superficial Neuromodulation in Dysautonomia in Women with Post-COVID-19 Condition: A Pilot Study.Brain sciences · 2025Article
- Association of homoarginine with arginine and disease severity in COVID-19 patients.Amino acids · 2025Article
- Trends in chronic neck and low back pain prevalence in Spain (2006-2020): differences by sex, age, and social class.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Observational
- Zoom-Delivered Empowered Relief for Chronic Pain: Observational Longitudinal Pilot Study Exploring Feasibility and Pain-Related Outcomes in Patients on Long-Term Opioids.JMIR formative research · 2025Observational
- A crossZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The COVID-19 pandemic transformed everyday life, but the implications were most impactful for vulnerable populations, including patients with chronic pain. Moreover, persistent pain is increasingly recognised as a key manifestation of long COVID. This narrative review explores the consequences of the COVID-19 pandemic for chronic pain. Publications were identified related to the COVID-19 pandemic influence on the burden of chronic pain, development of new-onset pain because of long COVID with proposed mechanisms and COVID-19 vaccines and pain interventions. Broadly, mechanisms underlying pain due to SARS-CoV-2 infection could be caused by 'systemic inflammatory-immune mechanisms', 'direct neuropathic mechanisms' or 'secondary mechanisms due to the viral infection or treatment'. Existing chronic pain populations were variably impacted and social determinants of health appeared to influence the degree of effect. SARS-CoV-2 infection increased the absolute numbers of patients with pain and headache. In the acute phase, headache as a presenting symptom predicted a milder course. New-onset chronic pain was reportedly common and likely involves multiple mechanisms; however, its prevalence decreases over time and symptoms appear to fluctuate. Patients requiring intensive support were particularly susceptible to long COVID symptoms. Some evidence suggests steroid exposure (often used for pain interventions) may affect vaccine efficacy, but there is no evidence of clinical repercussions to date. Although existing chronic pain management could help with symptomatic relief, there is a need to advance research focusing on mechanism-based treatments within the domain of multidisciplinary care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.