Evidence map›Paper›PMID 35848190›Full record

ReviewZhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery2022

[Research progress of nanomaterials for intra-articular targeted drug delivery in treatment of osteoarthritis].

Lujie Zong, Qian Wu, Zhongchen Dong, Lixin Huang, Huilin Yang

Abstract readReview
In one paragraph

Review in Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lujie ZongDepartment of Orthopedics, the First Affiliated Hospital of Soochow University, Suzhou Jiangsu, 215000, P. R. China.
Qian WuDepartment of Orthopedics, the First Affiliated Hospital of Soochow University, Suzhou Jiangsu, 215000, P. R. China.
Zhongchen DongDepartment of Orthopedics, the First Affiliated Hospital of Soochow University, Suzhou Jiangsu, 215000, P. R. China.
Lixin HuangDepartment of Orthopedics, the First Affiliated Hospital of Soochow University, Suzhou Jiangsu, 215000, P. R. China.
Huilin YangDepartment of Orthopedics, the First Affiliated Hospital of Soochow University, Suzhou Jiangsu, 215000, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To review the research progress of intra-articular targeted delivery of nanomaterials in the treatment of osteoarthritis (OA). Methods: The domestic and foreign related literature on intra-articular targeted delivery of nanomaterials for the treatment of OA was extensively reviewed, and their targeting strategies were discussed and summarized. Results: Rapid drug clearance from the joint remains a critical limitation in drug efficacy. Nanocarriers can not only significantly improve the residence profiles of drugs in the joint, but also achieve targeted delivery of drugs to specific joint tissues through active or passive targeting strategies. Conclusion: With the continuous development of various emerging tissue- or cell-specific drugs, the targeted delivery of drugs with nanomaterials promise to realize the clinical translation of these drugs in the treatment of OA.

Indexed as

NanostructuresOsteoarthritisDrug Delivery SystemsHumansInjections, Intra-Articularintra-articular injectionnanomaterialsOsteoarthritistargeted delivery

Identifiers

PMID35848190
PMCPMC9288906

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.