Evidence map›Paper›PMID 35848106›Full record

ArticleACS applied bio materials2022

Monodispersed Sirolimus-Loaded PLGA Microspheres with a Controlled Degree of Drug-Polymer Phase Separation for Drug-Coated Implantable Medical Devices and Subcutaneous Injection.

Zilin Zhang, Ekanem E Ekanem, Mitsutoshi Nakajima, Guido Bolognesi, Goran T Vladisavljević

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied bio materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. PLGA-based long-acting injectable (LAI) formulations.Journal of controlled release : official journal of the Controlled Release Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Zilin ZhangDepartment of Chemical Engineering, Loughborough University, Loughborough LE11 3TU, U.K.
Ekanem E EkanemDepartment of Chemical Engineering, Loughborough University, Loughborough LE11 3TU, U.K.
Mitsutoshi NakajimaFaculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8572, Japan.ORCID 0000-0002-3453-2481
Guido BolognesiDepartment of Chemical Engineering, Loughborough University, Loughborough LE11 3TU, U.K.ORCID 0000-0002-2380-0794
Goran T VladisavljevićDepartment of Chemical Engineering, Loughborough University, Loughborough LE11 3TU, U.K.ORCID 0000-0002-8894-975X
Loughborough University · GBUniversity of Tsukuba · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monodispersed sirolimus (SRL)-loaded poly(lactic-

Indexed as

Lactic AcidPolyglycolic AcidInjections, SubcutaneousMicrospheresParticle SizePharmaceutical PreparationsPolylactic Acid-Polyglycolic Acid CopolymerProstheses and ImplantsSirolimusSolventsLactic AcidPharmaceutical PreparationsPolyglycolic AcidPolylactic Acid-Polyglycolic Acid CopolymerSirolimusSolventsbiodegradable polymercontrolled drug releasedrug deliverydrug-eluting medical devicespoly(lactic-co-glycolic acid)step microfluidic emulsification

Identifiers

PMID35848106
PMCPMC9382632
OpenAlexW4285588839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.