Evidence map›Paper›PMID 35848090›Full record

ArticleJournal of applied clinical medical physics2022

Quality assurance and long-term stability of a novel 3-in-1 X-ray system for brachytherapy.

Andre Karius, Juliane Szkitsak, Vasilios Boronikolas, Rainer Fietkau, Christoph Bert

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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  5. Is model-based dose calculation based on cone-beam computed tomography suitable for adaptive treatment planning in brachytherapy?Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andre KariusDepartment of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Juliane SzkitsakDepartment of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Vasilios BoronikolasAbteilung für medizinische Physik, Klinik für Strahlenheilkunde, Universitätsklinikum Freiburg, Freiburg im Breisgau, Deutschland.
Rainer FietkauDepartment of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Christoph BertDepartment of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

Funding

Deutsche ForschungsgemeinschaftFriedrich-Alexander-Universität Erlangen-Nürnberg
6 · The paper itself

Abstract

purposeA novel, mobile 3-in-1 X-ray system featuring radiography, fluoroscopy, and cone-beam computed tomography (CBCT) has been launched for brachytherapy recently. Currently, there is no quality assurance (QA) procedure explicitly applicable to this system equipped with innovative technologies such as dynamic jaws and motorized lasers. We developed a dedicated QA procedure and, based on its performance for a duration of 6 months, provide an assessment of the device's stability over time.

methodsWith the developed QA procedure, we assessed the system's planar and CBCT-imaging performance by investigating geometric accuracy, CT-number stability, contrast-noise-ratio, uniformity, spatial resolution, low-contrast detectability, dynamic range, and X-ray exposure using dedicated phantoms. Furthermore, we evaluated geometric stability by using the flexmap-approach and investigated the device's laser- and jaw-positioning accuracy with an in-house test phantom. CBCT- and planar-imaging protocols for pelvis, breast, and abdomen imaging were examined.

resultsPlanar- and CBCT-imaging performances were widely stable with a geometric accuracy ≤1 mm, CT-number stability of up to 46 HU, and uniformity variations of up to 48 HU over time. For planar imaging, low-contrast detectability and dynamic range exceeded current recommendations. Although geometric stability was considered tolerable, partly substantial positioning inaccuracies of up to more than 120 mm and -13 mm were obtained for lasers and jaws, respectively. X-ray exposure showed small variations of ≤0.56 μGy and ≤0.76 mGy for planar- and CBCT-imaging, respectively. The conductance of the QA procedure allowed a smooth evaluation of the system's overall performance.

conclusionWe developed a QA workflow for a novel 3-in-1 X-ray system allowing to assess the device's imaging and hardware performance. The system showed in general a reasonable imaging performance and stability over time, whereas improvements regarding laser and jaw accuracy are strictly required.

Indexed as

BrachytherapyCone-Beam Computed TomographyFluoroscopyHumansPhantoms, ImagingX-Rays3-in-1 X-ray systemcone-beam computed tomographyplanar imagingquality assurance

Identifiers

PMID35848090
PMCPMC9512339

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.