Evidence map›Paper›PMID 35848057›Full record

ArticleAlimentary pharmacology & therapeutics2022

Sugar-sweetened beverages, artificially sweetened beverages and natural juices and risk of inflammatory bowel disease: a cohort study of 121,490 participants.

Tian Fu, Hui Chen, Xuejie Chen, Yuhao Sun, Ying Xie, Minzi Deng, Therese Hesketh, Xiaoyan Wang, Jie Chen

Open access · hybridAbstract read
In one paragraph

Article in Alimentary pharmacology & therapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.

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  18. Is there an "optimal" diet for prevention of inflammatory bowel disease?JGH open : an open access journal of gastroenterology and hepatology · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Tian FuDepartment of Gastroenterology, The Third Xiangya Hospital of Central South University, Changsha, China.
Hui ChenSchool of Public Health, Zhejiang University School of Medicine, Hangzhou, China.ORCID 0000-0003-2866-7811
Xuejie ChenDepartment of Gastroenterology, The Third Xiangya Hospital of Central South University, Changsha, China.
Yuhao SunCentre for Global Health, Zhejiang University, Hangzhou, China.
Ying XieCentre for Global Health, Zhejiang University, Hangzhou, China.
Minzi DengDepartment of Gastroenterology, The Third Xiangya Hospital of Central South University, Changsha, China.
Therese HeskethCentre for Global Health, Zhejiang University, Hangzhou, China.
Xiaoyan WangDepartment of Gastroenterology, The Third Xiangya Hospital of Central South University, Changsha, China.ORCID 0000-0002-7281-1078
Jie ChenDepartment of Gastroenterology, The Third Xiangya Hospital of Central South University, Changsha, China.ORCID 0000-0002-4029-4192
Central South University · CNZhejiang University · CNUniversity College London · GB

Funding

Medical Research Council MC_PC_17228Medical Research Council MC_QA137853
6 · The paper itself

Abstract

backgroundInflammatory bowel diseases (IBD) have been related to high-sugar dietary patterns, but the associations of different types of beverages with IBD risk are largely unknown.

aimsTo examine any associations between intake of sugar-sweetened beverages, artificially sweetened beverages and natural juices and IBD risk

methodsThis cohort study included 121,490 participants in the UK Biobank who were free of IBD at recruitment. Intake of beverages was obtained from repeated 24-h diet recalls in 2009-2012. Cox proportional hazard models were used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) for associations of beverage intake with IBD risk.

resultsDuring a mean (standard deviation) follow-up of 10.2 (1.5) years, we documented 510 incident IBD cases, (143 Crohn's disease (CD) and 367 ulcerative colitis (UC)). Compared to non-consumers, participants consuming >1 unit per day of sugar-sweetened beverages were at significantly higher risk of IBD (HR 1.51, 95% CI 1.11-2.05), but the trend was non-significant (p-trend = 0.170). This association was significant for CD (HR 2.05, 95% CI 1.22-3.46), but not for UC (HR 1.31, 95% CI 0.89-1.92). We did not observe significant associations for the consumption of artificially sweetened beverages or natural juices.

conclusionsOur findings suggest an association between consumption of sugar-sweetened beverages, rather than artificially sweetened beverages or natural juices, and IBD risk.

Indexed as

Colitis, UlcerativeCrohn DiseaseSugar-Sweetened BeveragesArtificially Sweetened BeveragesBeveragesCohort StudiesHumansProspective StudiesSugarsSweetening AgentsSugarsSweetening Agents

Identifiers

PMID35848057
PMCPMC9546432
OpenAlexW4285730847

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.