Evidence map›Paper›PMID 35848051›Full record

ArticleJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2022

Cell Surface Calcium-Sensing Receptor Heterodimers: Mutant Gene Dosage Affects Ca

Mahvash A Goolam, Alice P Brown, Kimberly T Edwards, Karen J Gregory, Katie Leach, Arthur D Conigrave

Open access · hybridAbstract read
In one paragraph

Article in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Molecular regulation of calcium-sensing receptor (CaSR)-mediated signaling.Chronic diseases and translational medicine · 2024
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mahvash A GoolamSchool of Life and Environmental Sciences, Charles Perkins Centre (D17), University of Sydney, NSW, Australia.
Alice P BrownSchool of Life and Environmental Sciences, Charles Perkins Centre (D17), University of Sydney, NSW, Australia.
Kimberly T EdwardsSchool of Life and Environmental Sciences, Charles Perkins Centre (D17), University of Sydney, NSW, Australia.
Karen J GregoryMonash Institute of Pharmaceutical Sciences and Department of Pharmacology, Monash University, Parkville, Victoria, Australia.
Katie LeachMonash Institute of Pharmaceutical Sciences and Department of Pharmacology, Monash University, Parkville, Victoria, Australia.
Arthur D ConigraveSchool of Life and Environmental Sciences, Charles Perkins Centre (D17), University of Sydney, NSW, Australia.ORCID 0000-0002-7232-3891
The University of Sydney · AUMonash University · AU

Funding

Australian Research Council FT160100075Australian Research Council FT170100392National Health and Medical Research Council APP1085143National Health and Medical Research Council APP1138891
6 · The paper itself

Abstract

The calcium-sensing receptor is a homodimeric class C G protein-coupled receptor (GPCR) that senses extracellular Ca

Indexed as

HypercalcemiaHyperparathyroidism, PrimaryCalciumgamma-Aminobutyric AcidGene DosageHEK293 CellsHumansInfant, NewbornMutationReceptors, Calcium-SensingCalciumgamma-Aminobutyric AcidReceptors, Calcium-Sensingcalciumcalcium intracellular releasecalcium-sensing receptorcell cultureclass C GPCRGABAB sorting systemG protein-coupled receptor (GPCR)heterotrimeric G proteinmutant heterodimerssignaling in-trans

Identifiers

PMID35848051
PMCPMC9545990
OpenAlexW4285726142

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.