Evidence map›Paper›PMID 35848026›Full record

ArticleJournal of Alzheimer's disease : JAD2022

Subjective Cognitive Decline: Is a Resilient Personality Protective Against Progression to Objective Cognitive Impairment? Findings from Two Community-Based Cohort Studies.

Damaris Aschwanden, Angelina R Sutin, Thomas Ledermann, Martina Luchetti, Yannick Stephan, Amanda A Sesker, Xianghe Zhu, Antonio Terracciano

Abstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Personality and Transition From Mild Cognitive Impairment to Normal Cognition vs Dementia.Journal of the American Medical Directors Association · 2024
    Observational
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Damaris AschwandenDepartment of Geriatrics, Florida State University College of Medicine, Tallahassee, FL, USA.
Angelina R SutinDepartment of Behavioral Sciences and Social Medicine, Florida State University College of Medicine, Tallahassee, FL, USA.
Thomas LedermannDepartment of Human Development and Family Science, Florida State University College of Health and Human Sciences, Tallahassee, FL, USA.
Martina LuchettiDepartment of Behavioral Sciences and Social Medicine, Florida State University College of Medicine, Tallahassee, FL, USA.
Yannick StephanEuromov, University of Montpellier, Montpellier, France.
Amanda A SeskerDepartment of Behavioral Sciences and Social Medicine, Florida State University College of Medicine, Tallahassee, FL, USA.
Xianghe ZhuDepartment of Geriatrics, Florida State University College of Medicine, Tallahassee, FL, USA.
Antonio TerraccianoDepartment of Geriatrics, Florida State University College of Medicine, Tallahassee, FL, USA.

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Prenatal and Early Life Antecedents of Personality: An Intergenerational Lifespan ApproachR01AG053297 · NIA · FLORIDA STATE UNIVERSITY · PI Angelina R Sutin · 2017 to 2026
$4.3M
Personality and Dementia: Mechanisms and TrajectoriesR01AG068093 · NIA · FLORIDA STATE UNIVERSITY · PI TERRACCIANO, ANTONIO · 2020 to 2024
$3.0M
NIA NIH HHS R01 AG053297NIA NIH HHS R01 AG068093NIA NIH HHS U01 AG009740
6 · The paper itself

Abstract

backgroundSubjective cognitive decline (SCD) is related to personality functioning and risk of subsequent objective cognitive impairment.

objectiveThe aim of this study was to examine whether lower neuroticism and higher conscientiousness-resilient personality traits-protect against conversion from SCD to objective cognitive impairment in two longitudinal community-based cohorts.

methodsData from the Health and Retirement Study (N = 1,741, Mean age = 68.64 years, Follow-up mean = 7.34 years) and the National Health and Aging Trends Survey (N = 258, Mean age = 79.34 years, Follow-up mean = 4.31 years) were analyzed using Cox regression analysis, controlling for sociodemographic covariates, symptoms of anxiety and depression, and apolipoprotein ɛ4.

resultsThe pooled results showed that lower neuroticism and higher conscientiousness were associated with decreased risk of conversion from SCD to objective cognitive impairment.

conclusionAmong individuals with SCD, those with a resilient personality may have more cognitive and psychological reserve to maintain cognitive functioning and delay conversion to objective cognitive impairment. The findings further contribute to a better understanding of personality along the cognitive continuum: The observed effect sizes were smaller than those reported in cognitively normal individuals but larger than in individuals with mild cognitive impairment. Personality could provide useful information to identify individuals with SCD who may develop objective cognitive impairment-namely those who hold a vulnerable personality (higher neuroticism, lower conscientiousness).

Indexed as

Cognitive DysfunctionAgedApolipoprotein E4Cohort StudiesHumansPersonalityPersonality DisordersApolipoprotein E4Conscientiousnessneuroticismprogression to cognitive impairmentresilient personalitysubjective cognitive decline

Identifiers

PMID35848026
PMCPMC9843496

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.