Evidence map›Paper›PMID 35847864›Full record

ArticleFrontiers in oncology2022

Whole-Genome DNA Methylation Sequencing Reveals Epigenetic Changes in Myelodysplastic Syndromes.

Jing-Dong Zhou, Zi-Jun Xu, Ye Jin, Xin-Long Zhang, Yu Gu, Ji-Chun Ma, Xiang-Mei Wen, Jiang Lin, Ting-Juan Zhang, Jun Qian

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Epigenetic alterations in Myeloid Malignancies.Advances in experimental medicine and biology · 2026
    Review
  4. Pannexin channels in inflammation and tumorigenesis.Frontiers in cell and developmental biology · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Jing-Dong ZhouDepartment of Hematology, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Zi-Jun XuZhenjiang Clinical Research Center of Hematology, Zhenjiang, China.
Ye JinDepartment of Hematology, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Xin-Long ZhangDepartment of Hematology, The People's Hospital of Danyang, Zhenjiang, China.
Yu GuDepartment of Hematology, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Ji-Chun MaZhenjiang Clinical Research Center of Hematology, Zhenjiang, China.
Xiang-Mei WenZhenjiang Clinical Research Center of Hematology, Zhenjiang, China.
Jiang LinZhenjiang Clinical Research Center of Hematology, Zhenjiang, China.
Ting-Juan ZhangZhenjiang Clinical Research Center of Hematology, Zhenjiang, China.
Jun QianDepartment of Hematology, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Shanghai Clinical Research Center · CNZhanjiang Experimental Station · CNAffiliated Hospital of Jiangsu University · CNFuyang City People's Hospital · CNJiangsu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epigenetic dysregulation of cancer-associated genes has been identified to contribute to the pathogenesis of myelodysplastic syndromes (MDS). However, few studies have elucidated the whole-genome DNA methylation in the initiation pathogenesis of MDS. Reduced representation bisulfite sequencing was performed in five

Indexed as

epigeneticsgenomeLEPmethylationmyelodysplastic syndromes

Identifiers

PMID35847864
PMCPMC9277050
OpenAlexW4283691096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.