Evidence map›Paper›PMID 35847822›Full record

ReviewFrontiers in medicine2022

Postoperative Nausea and Vomiting in Female Patients Undergoing Breast and Gynecological Surgery: A Narrative Review of Risk Factors and Prophylaxis.

Marco Echeverria-Villalobos, Juan Fiorda-Diaz, Alberto Uribe, Sergio D Bergese

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06137027 (Sublingual Cannabidiol Oil Extract for Prevention of Postoperative Nausea and Vomiting in Elective Gynaecological Patients at the University Hospital of the West Indies), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06137027 early_phase1unknown statusnot on this mapstarted 2023, after this paper: background citation

Sublingual Cannabidiol Oil Extract for Prevention of Postoperative Nausea and Vomiting in Elective Gynaecological Patients at the University Hospital of the West Indies (UHWI)

TypeinterventionalSponsorThe University of The West IndiesRan2023 to 2024Enrolled120ConditionsPostoperative Nausea and VomitingArmsCannabidiol Oil, Placebo
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
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  8. A study on the effect of clinical intervention of evidence-based nursing measures on complications in patients after breast-conserving surgery.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
    Trial
  9. Trial
  10. Review
  11. Article
  12. Article
  13. Die Anaesthesiologie · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Observational
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Marco Echeverria-VillalobosDepartment of Anesthesiology, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Juan Fiorda-DiazDepartment of Anesthesiology, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Alberto UribeDepartment of Anesthesiology, The Ohio State University Wexner Medical Center, Columbus, OH, United States.
Sergio D BergeseDepartment of Anesthesiology, Health Sciences Center, School of Medicine, Stony Brook University, New York, NY, United States.
The Ohio State University Wexner Medical Center · USStony Brook University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative nausea and vomiting (PONV) have been widely studied as a multifactorial entity, being of female gender the strongest risk factor. Reported PONV incidence in female surgical populations is extremely variable among randomized clinical trials. In this narrative review, we intend to summarize the incidence, independent predictors, pharmacological and non-pharmacological interventions for PONV reported in recently published clinical trials carried out in female patients undergoing breast and gynecologic surgery, as well as the implications of the anesthetic agents on the incidence of PONV. A literature search of manuscripts describing PONV management in female surgical populations (breast surgery and gynecologic surgery) was carried out in PubMed, MEDLINE, and Embase databases. Postoperative nausea and vomiting incidence were highly variable in patients receiving placebo or no prophylaxis among RCTs whereas consistent results were observed in patients receiving 1 or 2 prophylactic interventions for PONV. Despite efforts made, a considerable number of female patients still experienced significant PONV. It is critical for the anesthesia provider to be aware that the coexistence of independent risk factors such as the level of sex hormones (pre- and postmenopausal), preoperative anxiety or depression, pharmacogenomic pleomorphisms, and ethnicity further enhances the probability of experiencing PONV in female patients. Future RCTs should closely assess the overall risk of PONV in female patients considering patient- and surgery-related factors, and the level of compliance with current guidelines for prevention and management of PONV.

Indexed as

breast surgeryfemale gendergynecological surgerypostoperative nausea and vomitingrandomized clinical trial ERAS (Enhance Recovery After Surgery)

Identifiers

PMID35847822
PMCPMC9283686
OpenAlexW4283744506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.