Evidence map›Paper›PMID 35847727›Full record

ArticleEJHaem2020

Progressive substitution of posttransplant cyclophosphamide with bendamustine: A phase I study in haploidentical bone marrow transplantation.

Emmanuel Katsanis, Keri Maher, Denise J Roe, Richard J Simpson

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in EJHaem, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02996773 (A Phase I/Ib Study of Haploidentical Bone Marrow Transplant With Post-Transplant Cyclophosphamide and/or Bendamustine), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02996773 phase1completednot on this map

A Phase I/Ib Study of Haploidentical Bone Marrow Transplant With Post-Transplant Cyclophosphamide and/or Bendamustine

TypeinterventionalSponsorUniversity of ArizonaRan2016 to 2025Enrolled50ConditionsAcute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Myelodysplastic Syndromes, Chronic Myelogenous LeukemiaArmsBendamustine, Cyclophosphamide
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Emmanuel KatsanisDepartment of Pediatrics University of Arizona Tucson Arizona.ORCID https://orcid.org/0000-0003-1466-6965
Keri MaherDepartment of Medicine University of Arizona Tucson Arizona.
Denise J RoeThe University of Arizona Cancer Center Tucson Arizona.
Richard J SimpsonDepartment of Pediatrics University of Arizona Tucson Arizona.ORCID https://orcid.org/0000-0002-7064-6881
University of Arizona · US

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Dan Theodorescu · 1985 to 2026
$110.2M
NCI NIH HHS P30 CA023074
6 · The paper itself

Abstract

We have initiated a single center phase I study in patients with hematologic malignancies progressively substituting day +4 posttransplant cyclophosphamide (PT-CY) with bendamustine (PT-BEN) following myeloablative conditioning (MAC) and T-cell replete haploidentical bone marrow transplantation (haplo-BMT). We report herein our interim analysis of our first three cohorts PT-CY (mg/kg)/PT-BEN (mg/m

Indexed as

haploidentical BMTmyeloablativeposttransplant bendamustine

Identifiers

PMID35847727
PMCPMC9176108
OpenAlexW3031614553

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.