Evidence map›Paper›PMID 35847629›Full record

ArticleFrontiers in veterinary science2022

Biomechanical and Microstructural Properties of Subchondral Bone From Three Metacarpophalangeal Joint Sites in Thoroughbred Racehorses.

Duncan J Pearce, Peta L Hitchens, Fatemeh Malekipour, Babatunde Ayodele, Peter Vee Sin Lee, R Chris Whitton

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Duncan J PearceFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Werribee, VIC, Australia.
Peta L HitchensFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Werribee, VIC, Australia.
Fatemeh MalekipourDepartment of Biomedical Engineering, The University of Melbourne, Parkville, VIC, Australia.
Babatunde AyodeleFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Werribee, VIC, Australia.
Peter Vee Sin LeeDepartment of Biomedical Engineering, The University of Melbourne, Parkville, VIC, Australia.
R Chris WhittonFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Werribee, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fatigue-induced subchondral bone (SCB) injury is common in racehorses. Understanding how subchondral microstructure and microdamage influence mechanical properties is important for developing injury prevention strategies. Mechanical properties of the disto-palmar third metacarpal condyle (MCIII) correlate poorly with microstructure, and it is unknown whether the properties of other sites within the metacarpophalangeal (fetlock) joint are similarly complex. We aimed to investigate the mechanical and structural properties of equine SCB from specimens with minimal evidence of macroscopic disease. Three sites within the metacarpophalangeal joint were examined: the disto-palmar MCIII, disto-dorsal MCIII, and proximal sesamoid bone. Two regions of interest within the SCB were compared, a 2 mm superficial and an underlying 2 mm deep layer. Cartilage-bone specimens underwent micro-computed tomography, then cyclic compression for 100 cycles at 2 Hz. Disto-dorsal MCIII specimens were loaded to 30 MPa (

Indexed as

equinehysteresismetacarpusmicrodamagestiffnesssubchondral bone

Identifiers

PMID35847629
PMCPMC9277662

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.