ReviewOxidative medicine and cellular longevity2022
Selenium Status and Its Antioxidant Role in Metabolic Diseases.
Review in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- Pooled it
- Trial
- Modulatory Effects of Essential Trace Elements on Glycemic Biomarkers in Toxic Metal-Induced Associated Diabetes.Biological trace element research · 2026Article
- Preventive and Ameliorative Effects of Se- and Zn-Biofortified Chickpeas on MAFLD-Related Metabolic Disturbances.Foods (Basel, Switzerland) · 2026Article
- Computational analysis and expression profiling of the Sulfate Transporter gene family in tomato under selenium and abiotic stress treatment.BMC plant biology · 2026Article
- Determination of the Modulatory Effects of Selenium-Enriched Egg Powder on the Physiological Immune Response and Cecal Microbiota of Kunming Mice.Foods (Basel, Switzerland) · 2026Article
- Micronutrient Profiles and Anxiety in Adolescents with Non-Structural Palpitations: A Case-Control Study.Nutrients · 2026Article
- Article
- Natural extract-derived compounds for the treatment of hematological diseases through modulation of the bone marrow microenvironment.Frontiers in chemistry · 2026Review
- Selenium intake and a selenium-centered nutrient pattern are inversely associated with remnant cholesterol among older women in rural China: partial mediation by tumor necrosis factor-α.BMC geriatrics · 2025Article
- A Comprehensive Review of Selenium as a Key Regulator in Thyroid Health.Biological trace element research · 2025Review
- Extractive Electrospray Ionization Mass Spectrometry for Rapid Analysis of Organic and Inorganic Selenium in Honey.Molecules (Basel, Switzerland) · 2025Article
- Micronutrient antioxidant supplementation alleviates valproic acid-induced oxidative stress and male infertility via the NRF2/HO-1 pathway.Redox biology · 2025Article
- Review
- A Review of Bioactive Components and Pharmacological Effects ofFood science & nutrition · 2025Review
- Selenium: 48-year journey of global clinical trials.Molecular and cellular biochemistry · 2025Review
- Article
- The effect of supplementing rosemary essential oil and selenium yeast in the diet on sperm parameters and antioxidant activity of semen in older broiler breeder roosters.Iranian journal of veterinary research · 2025Article
- Oxidative stress: from molecular studies to clinical intervention strategies.Frontiers in molecular biosciences · 2025Review
- Mediation Effect of Oxidative Stress on Association Between Selenium Intake and Cognition in American Adults.Nutrients · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Selenium (Se), in the form of selenoproteins, is an essential micronutrient that plays an important role in human health and disease. To date, there are at least 25 selenoproteins in humans involved in a wide variety of biological functions, including mammalian development, metabolic progress, inflammation response, chemoprotective properties, and most notably, oxidoreductase functions. In recent years, numerous studies have reported that low Se levels are associated with increased risk, poor outcome, and mortality of metabolic disorders, mainly related to the limited antioxidant defense resulting from Se deficiency. Moreover, the correlation between Se deficiency and Keshan disease has received considerable attention. Therefore, Se supplementation as a therapeutic strategy for preventing the occurrence, delaying the progression, and alleviating the outcomes of some diseases has been widely studied. However, supranutritional levels of serum Se may have adverse effects, including Se poisoning. This review evaluates the correlation between Se status and human health, with particular emphasis on the antioxidant benefits of Se in metabolic disorders, shedding light on clinical treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.