ArticleCommunications medicine2022
The relationship between the gut microbiome and the risk of respiratory infections among newborns.
Article in Communications medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Changes in gut microbiota composition following water kefir consumption in healthy adults.Scientific reports · 2026Article
- The association of maternal and infant early gut microbiota with respiratory infections in infants.Pediatric research · 2026Article
- Initial insights into perinatal gut microbiome and early infantile respiratory tract infections.Pediatric research · 2026Article
- The gut microbiota and sleep in infants: a focus on diurnal rhythmicity patterns.Gut microbes reports · 2026Article
- Prenatal Exposure to Proton Pump Inhibitors and Risk of Serious Infections in Offspring During the First Year of Life: A Nationwide Cohort Study.Drug safety · 2025Article
- Functional Analysis of TAAR1 Expression in the Intestine Wall and the Effect of Its Gene Knockout on the Gut Microbiota in Mice.International journal of molecular sciences · 2024Article
- Nourishing the Infant Gut Microbiome to Support Immune Health: Protocol of SUN (Seeding Through Feeding) Randomized Controlled Trial.JMIR research protocols · 2024Article
- Global prevalence of infections in newborns with respiratory complications: systematic review and meta-analysis.Iranian journal of microbiology · 2024Article
- Effects of Contagious Respiratory Pathogens on Breath Biomarkers.Antioxidants (Basel, Switzerland) · 2024Article
- Fecal shedding of SARS-CoV-2 in infants born to SARS-CoV-2 positive mothers: a pilot study.PeerJ · 2024Article
- Human microbiome variation associated with race and ethnicity emerges as early as 3 months of age.PLoS biology · 2023Article
- Early-life exposure to per- and polyfluoroalkyl substances and infant gut microbial composition.Environmental epidemiology (Philadelphia, Pa.) · 2023Article
- The relationship between the gut microbiome and the risk of respiratory infections among newborns.Communications medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 6 institutions in 1 country.
Funding
Abstract
Background: Emerging evidence points to a critical role of the developing gut microbiome in immune maturation and infant health; however, prospective studies are lacking. Methods: We examined the occurrence of infections and associated symptoms during the first year of life in relation to the infant gut microbiome at six weeks of age using bacterial 16S rRNA V4-V5 gene sequencing ( Results: Here we show higher infant gut microbiota alpha diversity was associated with an increased risk of infections or respiratory symptoms treated with a prescription medicine, and specifically upper respiratory tract infections. Among vaginally delivered infants, a higher alpha diversity was associated with an increased risk of all-cause wheezing treated with a prescription medicine and diarrhea involving a visit to a health care provider. Positive associations were specifically observed with Conclusion: Our findings suggest that intestinal microbial diversity and the relative abundance of key taxa in early infancy may influence susceptibility to respiratory infection, wheezing, and diarrhea.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.