ReviewAnnals of pediatric cardiology
Patent foramen ovale in children: Unique pediatric challenges and lessons learned from adult literature.
Review in Annals of pediatric cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.
- Systematic review of case series and case reports on pediatric pulmonary embolism.Journal of medical case reports · 2025Pooled it
- Are we Adhering to Guidelines for Follow-up Imaging in Neonates with Simple Congenital Heart Defects? What are the Healthcare Costs of Non-adherence?Pediatric cardiology · 2026Article
- Cardiac involvement in neurofibromatosis type 1: real-world baseline and follow-up findings from a tertiary single-center cohort.European journal of pediatrics · 2026Article
- Unique One-Stage Procedure: Simultaneous Patent Foramen Ovale Closure and Resection of Wilms Tumor With Vena Cava Thrombus in a 5-Year-Old.Clinical case reports · 2026Article
- Transcatheter Patent Foramen Ovale Closure and Complete Remission of Migraine in Children: A Single-Center Retrospective Cohort Study.Pediatric cardiology · 2026Article
- Patent Foramen Ovale in Children: A Review of Epidemiological Characteristics, Natural Course, and Intervention Strategies.Children (Basel, Switzerland) · 2025Review
- Rare Pediatric Posterior Stroke Case Report with Discussion of Brainstem Lesions.Neurology international · 2025Article
- Patent Foramen Ovale in Children: A Review of Recent Progress.Pediatric cardiology · 2025Review
- Clinical efficacy of percutaneous closure of patent foramen ovale in children diagnosed with migraine.Frontiers in cardiovascular medicine · 2025Article
- Impact of patent foramen ovale on short-term outcomes in children with biliary atresia undergoing living donor liver transplantation: a retrospective cohort study.BMC anesthesiology · 2023Article
- Patent foramen ovale with cryptogenic stroke: A case report.Medicine internationalArticle
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 14 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A patent foramen ovale (PFO) is a frequent incidental finding during echocardiography in otherwise healthy children. In most healthy children with a diagnosis of isolated incidental PFO, no further follow-up or intervention is necessary. In some children, PFO is associated with certain clinical syndromes such as cryptogenic stroke, decompression sickness, migraine, and platypnea-orthodeoxia syndrome. This review discusses PFO anatomy, diagnostic imaging, PFO-associated clinical situations, management options, and the role of PFO in certain congenital heart disease. This review also highlights the current deficiency of pediatric data guiding management of these uncommon but important PFO-associated conditions. Future multicenter randomized controlled studies are necessary to guide the management of these unique and challenging PFO-associated conditions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.