Evidence map›Paper›PMID 35847365›Full record

ArticleJournal of oncology2022

Treatment Response and Conditional Survival in Advanced Pancreatic Cancer Patients Treated with FOLFIRINOX: A Multicenter Cohort Study.

Fleur van der Sijde, Jacob L van Dam, Bas Groot Koerkamp, Brigitte C M Haberkorn, Marjolein Y V Homs, Daniëlle Mathijssen, Marc G Besselink, Johanna W Wilmink, Casper H J van Eijck

Open access · hybridAbstract read
In one paragraph

Article in Journal of oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. The value of FOLFIRINOX in advanced pancreatic cancer: balancing efficacy, toxicity, and quality of life.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  11. In vitro characterisation of [EJNMMI radiopharmacy and chemistry · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Fleur van der SijdeDepartment of Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.ORCID https://orcid.org/0000-0002-0634-4918
Jacob L van DamDepartment of Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.ORCID https://orcid.org/0000-0002-6947-9035
Bas Groot KoerkampDepartment of Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.ORCID https://orcid.org/0000-0003-1917-6973
Brigitte C M HaberkornDepartment of Medical Oncology, Maasstad Hospital, Rotterdam, Netherlands.
Marjolein Y V HomsDepartment of Medical Oncology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.
Daniëlle MathijssenDepartment of Medical Oncology, Franciscus Gasthuis, Rotterdam, Netherlands.
Marc G BesselinkDepartment of Surgery, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.ORCID https://orcid.org/0000-0003-2650-9350
Johanna W WilminkDepartment of Medical Oncology, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.ORCID https://orcid.org/0000-0002-1677-1278
Casper H J van EijckDepartment of Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands.ORCID https://orcid.org/0000-0002-9511-2157
Erasmus MC · NLAmsterdam University Medical Centers · NLMaasstad Ziekenhuis · NLSint Franciscus Gasthuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: FOLFIRINOX chemotherapy is the current Dutch standard of care for locally advanced (LAPC) and metastatic pancreatic cancer (PDAC) patients with good performance status. The objective of this study was to evaluate real-world response rates and survival in advanced PDAC and to assess conditional survival after FOLFIRINOX. Methods: A multicenter, retrospective cohort study was conducted in four hospitals in the Netherlands. Consecutive patients with LAPC or metastatic PDAC, treated with FOLFIRINOX, were included. Results: Between 2012 and 2018, 284 patients were included:

Identifiers

PMID35847365
PMCPMC9283068
OpenAlexW4284890922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.