Evidence map›Paper›PMID 35847364›Full record

ArticleJournal of oncology2022

The HBV Specially-Related Long Noncoding RNA HBV-SRL Involved in the Pathogenesis of Hepatocellular Carcinoma.

Cunzhen Zhang, Lei Lu, Haibei Xin, Minfeng Zhang, Zhiwen Ding, Qiaomei Li, Kuang Chen, Minggen Hu, Shupeng Liu, Nan Li

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Cunzhen ZhangDepartment of Hepatic Surgery I (Ward I) Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.ORCID https://orcid.org/0000-0002-0511-8417
Lei LuChanghai Hospital, Second Military Medical University, Shanghai, China.ORCID https://orcid.org/0000-0003-3273-0115
Haibei XinDepartment of Hepatic Surgery I (Ward I) Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.ORCID https://orcid.org/0000-0002-8476-5451
Minfeng ZhangDepartment of Hepatic Surgery I (Ward I) Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.ORCID https://orcid.org/0000-0001-5633-1958
Zhiwen DingDepartment of Hepatic Surgery I (Ward I) Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.ORCID https://orcid.org/0000-0002-5607-4143
Qiaomei LiDepartment of Hepatic Surgery I (Ward I) Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.ORCID https://orcid.org/0000-0003-0886-149X
Kuang ChenFaculty of Hepato-Pancreato-Biliary Surgery, Chinese PLA General Hospital, Beijing, China.ORCID https://orcid.org/0000-0003-1874-3630
Minggen HuFaculty of Hepato-Pancreato-Biliary Surgery, Chinese PLA General Hospital, Beijing, China.ORCID https://orcid.org/0000-0001-7933-7850
Shupeng LiuDepartment of Obstetrics and Gynecology, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.ORCID https://orcid.org/0000-0002-9276-7086
Nan LiDepartment of Hepatic Surgery I (Ward I) Shanghai Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.ORCID https://orcid.org/0000-0001-6547-0650
Second Military Medical University · CNChinese PLA General Hospital · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis B virus (HBV) is one of the major risk factors for HCC (hepatocellular carcinoma) occurrence with a diverse role in the pathogenesis of HCC. More works need to be performed to elucidate a more thorough understanding of the molecular mechanisms involving in HBV-induced HCC, although some mechanisms such as genome integration have been reported. In the present study, aberrantly expressed lncRNAs were identified between HCC tumor tissues with or without HBV infection. Among these molecules, HBV specially-related long noncoding RNA (HBV-SRL) was further found to correlate with poor prognosis and a shorter overall survival time in HCC patients with HBV infection. Additionally, HBV-SRL was found function as oncogene by upregulating the NF-

Identifiers

PMID35847364
PMCPMC9286890
OpenAlexW4284973041

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.