Evidence map›Paper›PMID 35847222›Full record

ArticleFrontiers in neurology2022

Prediction of Long-Term Restenosis After Carotid Endarterectomy Using Quantitative Magnetic Resonance Angiography.

Lukas Andereggen, Sepideh Amin-Hanjani, Jürgen Beck, Markus M Luedi, Jan Gralla, Gerrit A Schubert, Angelo Tortora, Robert H Andres, Marcel Arnold, Andreas Raabe and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Lukas AndereggenDepartment of Neurosurgery, Kantonsspital Aarau, Aarau, Switzerland.
Sepideh Amin-HanjaniDepartment of Neurosurgery, The University of Illinois at Chicago, Chicago, IL, United States.
Jürgen BeckDepartments of Neurosurgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Markus M LuediDepartment of Anaesthesiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Jan GrallaDepartment of Neuroradiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Gerrit A SchubertDepartment of Neurosurgery, Kantonsspital Aarau, Aarau, Switzerland.
Angelo TortoraDepartment of Neurosurgery, Kantonsspital Aarau, Aarau, Switzerland.
Robert H AndresFaculty of Medicine, University of Bern, Bern, Switzerland.
Marcel ArnoldDepartment of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Andreas RaabeDepartments of Neurosurgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Michael ReinertFaculty of Medicine, University of Bern, Bern, Switzerland.
University Hospital of Bern · CHKantonsspital Aarau · CHHirslanden Klinik St. Anna · CHUniversity Medical Center Freiburg · DEUniversity of Bern · CHUniversity of Illinois Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: To detect restenosis after carotid endarterectomy (CEA), long-term monitoring is required. However, non-selective follow-up is controversial and can be limited by costs and logistical considerations. Objective: To examine the value of immediate perioperative vessel flow measurements after CEA using quantitative magnetic resonance angiography (QMRA) to detect patients at risk of long-term restenosis. Methods: A prospective cohort study with long-term sonographic follow-up after CEA for symptomatic internal carotid artery stenosis (ICAs) > 50%. In all patients, vessel flow has been assessed both pre- and postoperatively using QMRA within ±3 days of surgery. Data on QMRA assessment were analyzed to identify patients at risk of restenosis for up to 10 years. Results: Restenosis was recorded in 4 of 24 patients (17%) at a median follow-up of 6.8 ± 2.6 years. None of them experienced an ischemic event. Perioperative flow differences were significantly greater in patients without long-term restenosis, both for the ipsilateral ICA ( Conclusion: Our preliminary findings suggest that QMRA-based mean flow increases after CEA may be predictive of restenosis over the long term. Perioperative QMRA assessment could become an operator-independent screening tool to identify a subgroup of patients at risk for restenosis, in whom long-term monitoring is advised.

Indexed as

carotid artery stenosiscarotid endarterectomycerebral blood flowquantitative phase-contrast MR angiographyrestenosis

Identifiers

PMID35847222
PMCPMC9279565
OpenAlexW4283730187

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.